Kinetics and Mechanisms: Oxidation Mechanisms of Some Selected Sulfur Compounds

动力学和机理：一些选定的硫化合物的氧化机理

• 批准号: 9632592
• 负责人: Reuben Simoyi
• 金额: $ 30万
• 依托单位: West Virginia University Research Corporation
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-07-01 至 2000-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9632592&HistoricalAwards=false
• 关键词: Kinetics; Mechanisms; Oxidation; Some; Selected

Dr. Reuben Simoyi, Department of Chemistry, West Virginia University, is supported by the Inorganic, Bioinorganic, and Organometallic Program of the Chemistry Division for studies of the oxidation mechanisms of sulfur compounds. Dr. Simoyi will study the kinetics and mechanisms of oxidation of selected sulfur compounds including thioureas, sulfinic acids, sulfonic acids, sulfide, and dimethyl sulfide. Oxidation of biologically relevant sulfur containing compounds including taurine, cysteine, isethionic acid, methionine and glutathione will also be investigated. The ultimate goal is a more complete description of chemical oscillators involving sulfur compounds, and an understanding of the pattern formation and symmetry-breaking bifurcations of these compounds. Techniques such as stopped and continuous flow methods, relaxation spectra, turbidimetry, EPR and NMR will be utilized. These systems are relevant to an understanding of sulfur abatement procedures in environmental pollution, and the amino acid studies may provide fundamental insights into their physiological importance. Sulfur is a unique element in the periodic table because it can occur in widely varying oxidation states (from -2 to +6), and it is thus quite reactive with metals, nonmetals and with organic compounds. These characteristics contribute to the environmental concerns associated with oxides of sulfur, which themselves are major atmospheric pollutants which can cause acid rain. The detailed reactivity of these and other sulfur compounds, especially those with environmental and biological significance, is not well understood. This project will help to elucidate the unusual reactivity patterns observed for these sulfur compounds, and will thus contribute to a broader understanding of their role in these important areas.

西弗吉尼亚大学化学系的 Reuben Simoyi 博士得到化学系无机、生物无机和有机金属项目的支持，研究硫化合物的氧化机制。 Simoyi 博士将研究选定硫化合物的氧化动力学和机制，包括硫脲、亚磺酸、磺酸、硫化物和二甲硫醚。 还将研究生物相关的含硫化合物（包括牛磺酸、半胱氨酸、羟乙基磺酸、蛋氨酸和谷胱甘肽）的氧化。 最终目标是更完整地描述涉及硫化合物的化学振荡器，并了解这些化合物的模式形成和对称破缺分岔。 将利用诸如停流法和连续流法、弛豫光谱、比浊法、EPR 和 NMR 等技术。这些系统与了解环境污染中的硫减排程序相关，氨基酸研究可以提供对其生理重要性的基本见解。 硫是元素周期表中的一种独特元素，因为它可以以多种氧化态（从 -2 到 +6）存在，因此与金属、非金属和有机化合物具有很强的反应性。这些特性加剧了与硫氧化物相关的环境问题，硫氧化物本身是可导致酸雨的主要大气污染物。 这些和其他硫化合物的详细反应性，特别是那些具有环境和生物学意义的化合物，尚不清楚。 该项目将有助于阐明这些硫化合物观察到的不寻常的反应模式，从而有助于更广泛地了解它们在这些重要领域中的作用。