Genetic Structure of a Primate Hybrid Zone

灵长类杂交区的遗传结构

• 批准号: 9615150
• 负责人: Clifford Jolly
• 金额: $ 40.57万
• 依托单位: New York University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-03-15 至 2002-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9615150&HistoricalAwards=false
• 关键词: Genetic; Structure; Primate; Hybrid; Zone

Jolly/Disotell/Phillips-Conroy When two natural populations interbreed, they tend to become genetically homogenized. If, however, individuals of mixed ancestry are relatively unfit, a narrow, intervening hybrid zone may persist for generations, filtering gene-flow between the populations. Many such hybrid zones are known, but few involve primates, even though hybridization was probably important in human prehistory. Our study brings together investigators at New York University, Washington University in St. Louis, and Addis Ababa University, Ethiopia. It combines powerful, new techniques of genetic analysis with field observation to investigate hybridization between two baboon populations, strikingly different in both behavior and appearance, whose ranges meet in Ethiopia. We have already collected and stored DNA from about a thousand baboons, of four generations. In three more field seasons we shall complete this dataset, and clarify ecological influences on hybridization by mapping the hybrid zone more widely. Each animal will be typed for hypervariable DNA markers. Their distribution will show how social behavior affects the genetic structure of the populations, reveal patterns of inter-group migration, and indicate the darwinian fitness of cross-breeders and their offspring. The result will be a unique picture of the dynamics of natural hybridization and the genetics of evolutionary divergence.

Jolly/Disotell/Phillips-Conroy 当两个自然种群杂交时，它们往往会变得基因同质化。 然而，如果混合血统的个体相对不适合，一个狭窄的、干预性的杂交区可能会持续几代，过滤种群之间的基因流。 已知许多这样的杂交区域，但很少涉及灵长类动物，尽管杂交可能在人类史前时期很重要。 我们的研究汇集了纽约大学、圣路易斯华盛顿大学和埃塞俄比亚亚的斯亚贝巴大学的研究人员。 它将强大的遗传分析新技术与实地观察相结合，研究两个狒狒种群之间的杂交，这两个狒狒种群在行为和外观上都截然不同，它们的分布范围都在埃塞俄比亚。 我们已经收集并储存了四代约一千只狒狒的 DNA。 再过三个田间季节，我们将完成该数据集，并通过更广泛地绘制杂交区地图来阐明生态对杂交的影响。 每只动物都将进行高变 DNA 标记分型。 它们的分布将显示社会行为如何影响种群的遗传结构，揭示群体间迁移的模式，并表明杂交育种者及其后代的达尔文适应性。 其结果将是一幅关于自然杂交动态和进化分歧遗传学的独特图景。