Next Generation Photocatalysis for Chemical Synthesis and Manufacture

用于化学合成和制造的下一代光催化

• 批准号: FT220100345
• 负责人: A/Prof Anastasios Polyzos
• 金额: $ 64.53万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2023
• 资助国家: 澳大利亚
• 起止时间: 2023-06-19 至 2027-06-18
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT220100345
• 关键词: Next; Generation; Photocatalysis; Chemical; Synthesis

This project aims to discover new methods for the activation of energy demanding bonds in organic molecules as a general strategy in chemical synthesis. A key conceptual advance in this project is the development of multiphoton photoredox catalysis as a powerful tool to activate traditionally unreactive, yet abundant chemical bonds in organic molecules including C-H bonds in alkane and olefin feedstocks. With application in fields that range from fine chemical production to drug discovery, the overarching aim of this research is to establish new bond activation reactions and to demonstrate translations to the invention of new pharmaceuticals, agrochemicals and advanced chemical manufacturing processes that will have societal impact.

该项目旨在发现激活有机分子中能量需求键的新方法，作为化学合成的一般策略。该项目的一个关键概念进展是开发多光子光氧化还原催化作为一种​​强大的工具来激活有机分子中传统上不反应但丰富的化学键，包括烷烃和烯烃原料中的C-H键。通过应用于从精细化学品生产到药物发现等领域，这项研究的首要目标是建立新的键活化反应，并证明对新药物、农用化学品和先进化学制造工艺的发明的转化，这些将产生社会影响。