Biomedical Image Processing Laboratory

生物医学图像处理实验室

• 批准号: 9203294
• 负责人: Edward Egelman
• 金额: $ 5.6万
• 依托单位: University of Minnesota-Twin Cities
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-05-01 至 1995-10-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9203294&HistoricalAwards=false
• 关键词: Biomedical; Image; Processing; Laboratory

The Biomedical Image Processing Laboratory at the University of Minnesota is a computational resource that will provide image analysis for basic research projects employing transmission electron microscopy, scanning electron microscopy, and confocal and conventional light microscopy. The resource is devoted to research and development in methods that can be used to elucidate biological structure by means of computational analysis and reconstruction of images of macromolecular assemblies, organelles and cells obtained by different microscopic techniques. In addition, the center will provide hardware and software to aid in the three-dimensional representation of the structures that are being studied. Collaborative projects, such as the study of bacteriophage morphogenesis and microtubule-tektin interactions, will take advantage of the facilities and the methods being developed. Further, the center will provide image analysis services to a large core of users at the University of Minnesota Medical School. The center will develop a second-generation on-line image analysis system for the transmission electron microscope, as well as a novel image analysis system for a low-voltage field-emission scanning electron microscope. The center will also take advantage of the fact that many different forms of microscopy and imaging generate similar problems and similar solutions. Thus, the research on methods within one of these areas may be easily applied to other areas within this center.

明尼苏达大学生物医学图像处理实验室是一个计算资源，将为采用透射电子显微镜、扫描电子显微镜、共焦和传统光学显微镜的基础研究项目提供图像分析。 该资源致力于研究和开发可用于通过计算分析和重建通过不同显微技术获得的大分子组装体、细胞器和细胞的图像来阐明生物结构的方法。 此外，该中心还将提供硬件和软件，以帮助对正在研究的结构进行三维表示。 噬菌体形态发生和微管-tektin相互作用的研究等合作项目将利用正在开发的设施和方法。 此外，该中心还将为明尼苏达大学医学院的大量核心用户提供图像分析服务。 该中心将开发第二代透射电子显微镜在线图像分析系统，以及新型低压场发射扫描电子显微镜图像分析系统。 该中心还将利用许多不同形式的显微镜和成像产生类似问题和类似解决方案的事实。因此，这些领域之一的方法研究可以很容易地应用于该中心的其他领域。