Genome evolution & adaptation of the multinuclear wheat stripe rust fungus

基因组进化

• 批准号: DP230100941
• 负责人: A/Prof Benjamin Schwessinger
• 金额: $ 31.56万
• 依托单位: The Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2023
• 资助国家: 澳大利亚
• 起止时间: 2023-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP230100941
• 关键词: Genome; evolution; adaptation; multinuclear; wheat

Animals and plants package their genomes into a single nucleus within each cell. In contrast, millions of fungal species accommodate multiple nuclei containing individual haploid genomes. It is currently unknown what the evolutionary implications are for this unusual genome division into multiple nuclei. Here we explore the evolutionary consequences of genome division into multiple nuclei for the first time by applying cutting edge genome biology tools and algorithms. The economically significant study system is the devastating wheat stripe rust fungus. This pathogen costs Australian farmers over $100 million a year. New understanding is expected to lead to better disease management, reduced fungicide applications, and increased yields.

动物和植物将其基因组包装成每个细胞内的一个核。相反，数百万个真菌物种可容纳多个含有单个单倍体基因组的核。目前尚不清楚这种不寻常的基因组分裂成多个核的进化意义。在这里，我们通过应用最先进的基因组生物学工具和算法，首次探讨了基因组分裂到多个核的进化后果。经济上重要的研究系统是毁灭性的小麦条纹锈菌。这种病原体每年造成澳大利亚农民的费用超过1亿美元。预计新的理解将导致更好的疾病管理，减少杀菌剂的应用和增加的产量。