Studies of Highly Reactive Molecules and Intermediates

高反应性分子及中间体的研究

• 批准号: 8921744
• 负责人: Thomas Hoye
• 金额: $ 79.5万
• 依托单位: University of Minnesota-Twin Cities
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-01-15 至 1995-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8921744&HistoricalAwards=false
• 关键词: Studies; Highly; Reactive; Molecules; Intermediates

The Organic Synthesis Program will support the continuation of the research of Dr. Paul G. Gassman. Dr. Gassman will continue his productive studies on highly strained systems and initiate work on the synthesis of ligands for transition metals. These will be used to change the apparent oxidation state of the metal. This increased control of the oxidation state will facilitate the synthesis of the increasingly complex materials needed by our economy. Studies in the area of organometallic chemistry will be centered on the use of X-ray photoelectron spectroscopy (XPS) to understand the electronic influence of ligands on complexed transition metals. New ligands will be prepared which are either more electron withdrawing or electron donating than currently available ligands. It is planned to prepare and study the properties of complexes which can serve as either oxidants or reductants as a function of the attached ligands. Work will continue on studies of trans-bicycloın.1.0!alkanes, strained paracyclophanes, and electron transfer from strained rings. New synthetic applications of electrochemical reductions will be explored. Improved excited state oxidants will be sought in an approach to the development of synthetically useful procedures for anti-Markovnikov addition of nucleophiles to simple olefins. Studies of radicals, anion radicals, cation radicals and cations will be carried out.

Gassman博士的有机合成计划我们的经济需要的金属。捐赠的蚂蚁作为附着的配体的功能将继续进行跨性别型氧化剂。将核寄生机构添加到简单的烯烃，阴离子自由基，阳离子自由基和阳离子中的抗马科夫尼科夫的合成方法。