Establishment of a Novel High Throughput Conditional Gene Trapping System

新型高通量条件基因捕获系统的建立

• 批准号: 202258
• 负责人: Jefferies Wilfred A
• 金额: $ 21.86万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-03-01 至 2013-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=202258&lang=en
• 关键词: Conditional Knock-Out Mice; Es Cell; Gene Trap; Mouse Model

1) To develop innovative scientific approaches to generate genome-wide conditional gene trap mutations in murine embryonic stem (ES) cells. 2) To develop efficient high-throughput approaches to identify the sites of gene trap insertion for each mutant con

1）开发创新的科学方法来在鼠中产生全基因组的条件基因陷阱突变 胚胎（ES）细胞。 2）开发有效的高通量方法来识别每个突变体con的基因陷阱插入的位点