甘肃汉族成人体成分与糖尿病、高血压和冠心病的相关性研究

Analysis of body composition is quantified and exploring the mysteries of human body, foreign scholars have been widely used in clinical medicine, epidemiology, nutrition and exercise physiology. Study of body composition in China has just started, at the preliminary stage, no body composition in patients with chronic diseases report. Chronic diseases in China has entered a "blowout", and more prominent in Gansu province, to find out pattern of body composition distribution among different populations in adults of Han nationality in Gansu, discuss on diabetes，hypertension and cardiovascular disease prevention and evaluation of the new system. This research intended application physical anthropology of method, selection body components four level model, on Gansu province Han adult (normal groups, and high risk groups and chronic disease patients) for vivo measurement, and biological resistance anti-analysis method (BIA) detection, and bone density measurement, and blood biochemical, method detection, electrocardiographic examination，get different crowd body components of data, established Gansu Han into human components database; research body components in different crowd of distribution features, discuss rules about normal crowd→high risk groups→chronic disease patients body components of changes pattern, for chronic disease of prevention , Creates a new body composition assessment system; we will compare the differences between different groups, from heredity, environment, diet, lifestyle, and so looking for its impact factor; we got spectrum of body components of a chronic disease groups.we are going to looking for the changes law of body components of three kinds of chronic diseases, in order to provide reference data for prevention and treatment of chronic diseases.

人体成分是量化性分析和探索人体奥秘，国外学者已经广泛应用于临床，流行病学，营养学和运动生理学等。但国内体成分的研究处于初级阶段，未见慢病患者体成分系统报道。国内慢病已进入"井喷"时期，而甘肃更为突出，为了解体成分在甘肃汉族成人不同人群分布规律，探讨糖尿病、高血压和冠心病预防评价体系。本研究拟应用体质人类学的方法，选用体成分四层次模型，对甘肃省汉族成人（正常人群、高危人群和3种慢病患者）进行活体测量、生物电阻抗分析法（BIA）、骨密度测量、血样生化、心电图等方法检测，获得不同人群体成分的数据，建立甘肃汉族成人体成分数据库；研究体成分在不同人群的分布特征，探讨正常人群→高危人群→慢病患者体成分的变化规律，为慢病的预防，创建新的体成分评价体系；比较不同人群体成分差异，从遗传、环境、膳食结构，生活方式等方面寻找其影响因素；获得3种慢病患病人群体成分谱，寻找其变化规律，为慢病的预防、治疗提供参考。

本项目应用体质人类学、医学人类学和流行病学方法，对甘肃陇东、兰州、临夏、天祝、河西5地汉族成人采用人体成分四层次研究模型，通过问卷调查、活体测量.、生物电阻抗分析法（BIA）检测、血样生化检测、骨密度测量、心电图和B超等检测。获得4653人（男：1924人，女：2729人）344322条信息数据，1429份血样，建立了甘肃汉族成人体质表型特征、人体成分、骨密度、疾病谱数据库和样本库，为甘肃汉族成人体质表型特征评价、比较不同人群体成分差异，从遗传、环境、膳食结构，生活方式等方面寻找其影响因素，为慢病的预防、诊治提供参考。

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