Exploring the development of endotoxin tolerance in sepsis.

探索脓毒症内毒素耐受的发展。

• 批准号: 197323
• 负责人: Pena Olga M
• 金额: $ 7.29万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-11-01 至 2011-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=197323&lang=en
• 关键词: Immunosupression; Infectious Diseases; Inflammation; Sepsis

The innate immune response is the first line of defense against microorganisms. However, if this response is highly stimulated, it can result in excessive inflammation that can lead to organ injury and high mortality. Sepsis, often caused by bacterial inf

先天免疫反应是针对微生物的第一道防线。但是，如果高度刺激了这种反应，则可能导致过度炎症，从而导致器官损伤和高死亡率。败血症，通常由细菌INF引起