Lung cancer therapy using genetically modified macrophages

使用转基因巨噬细胞治疗肺癌

• 批准号: 488420
• 负责人: Post Martin
• 金额: $ 71.33万
• 依托单位: Hospital for Sick Children (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2023
• 资助国家: 加拿大
• 起止时间: 2023-09-01 至 2028-09-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=488420&lang=en
• 关键词: Alveolar-Like Macrophages; Cd47/Sirpalpha Axis; Immunotherapy With Modified Alms; Lung Cancer Cells; Orthotopic Lung Cancer Models; Phagocytosis And Cell Death; Stem Cells

Lung cancer remains the leading cause of cancer death worldwide. Current therapies have not been effective in curbing this death rate. New therapies are urgently needed. We have created special lung immune cells in the lab from stem cells that are designe

肺癌仍然是全球癌症死亡的主要原因。目前的治疗方法未能有效控制死亡率。迫切需要新的疗法。我们在实验室中利用干细胞创建了特殊的肺部免疫细胞