Design of high performance antiviral and antibacterial cold spray coatings for continuous disinfection on high-touch surfaces

高性能抗病毒和抗菌冷喷涂涂层的设计，用于高接触表面的持续消毒

• 批准号: 571026-2021
• 负责人: Yue, StephenS
• 金额: $ 29.14万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Alliance Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=761074
• 关键词: Design; performance; antiviral; antibacterial; cold

The preventive measures currently applied to contain the transmission of SARS-CoV-2 by surfaces (i.e.'fomites') have highlighted the importance of surface disinfection. In order to limit transmission by fomites,most commercial buildings, schools and other public infrastructure have improved their cleaning and disinfection protocols and increased their frequencies, adding financial and logistical burdens to their operation. Therefore, there is a high demand for a reliable and economical solution that would provide passive and continuous disinfection on frequently touched surfaces. This project aims to continue our efforts, initiated in a project funded by a CRSNG-COVID-19 grant, in the design of high performance antiviral coatings for frequently touched surfaces. The research will focus on (1) the development of knowledge on the influence of properties of copper-based materials on the mechanisms of inactivation of viruses and bacteria to develop coatings with enhanced activities against a wide range of viruses and bacteria and (2) develop coatings that maintain their antiviral and antibacterial performance for years by withstanding normal conditions of use, including cleaning and disinfection protocols that use harsh chemicals. The project partners include McGill University, supplying Materials and Virus and Bacteria expertise, INRS bringing knowledge of surface interactions and NRC, working with McGill and INRS on materials and processing developments and helping the three collaborating companies industrialize and commercialize the findings. During the project, the powder company, 5N Plus will develop, based on the results obtained, a metallic powder having the composition and the properties optimal for the marketing of this application; Polycontrols will manufacture industrial demonstrations of the coating technology, produce coatings and commercialize coating systems for this application; Hatch Ltd. will respond to market demands with performance data and sustainability analysis, allowing it to upgrade public infrastructures with such coatings.

目前采用的预防措施包含表面（即'fomites'）传播SARS-COV-2，这突出了表面消毒的重要性。为了限制FOMITE的传播，大多数商业建筑，学校和其他公共基础设施都改善了清洁和消毒协议，并增加了其频率，从而增加了财务和后勤负担。因此，对可靠且经济的解决方案的需求很高，该解决方案将在经常接触的表面上提供被动和连续的消毒。该项目旨在继续我们的努力，该项目是在由CRSNG-COVID-19赠款资助的项目中发起的，该项目是针对经常感动的表面的高性能抗病毒涂料设计。这项研究将重点放在（1）知识的发展上，基于铜的材料对病毒和细菌失活的机制的影响，开发具有增强活动的涂料，以增强活性对广泛的病毒和细菌，以及（2）通过使用抗病毒和抗体性能来维护多年来使用的抗病毒和抗体性能，包括使用耐药的正常条件，包括使用清洁药物，包括使用疗法的化学效果，包括耐药的化学效果。该项目合作伙伴包括麦吉尔大学，提供材料，病毒和细菌专业知识，INR带来了有关表面互动和NRC的知识，与McGill和INR合作，从事材料和处理开发以及帮助三个合作公司将发现和商业化发现。在项目期间，根据获得的结果，将开发5N Plus的粉末公司，其构图和最佳属性对于该应用程序的营销而开发；多控制将制造涂料技术的工业演示，生产涂料并为此应用商业化涂料系统； Hatch Ltd.将通过绩效数据和可持续性分析来响应市场需求，从而可以通过此类涂料来升级公共基础设施。