Mechanisms of stem cell niches in gut development and inflammation

干细胞生态位在肠道发育和炎症中的机制

• 批准号: 478956
• 负责人: Kim Tae-Hee
• 金额: $ 69.11万
• 依托单位: Hospital for Sick Children (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2023
• 资助国家: 加拿大
• 起止时间: 2023-03-01 至 2028-03-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=478956&lang=en
• 关键词: Gastroenterology; Gut; Inflammation; Signalling; Stem Cell Niches

Gut stem cells are cells in the intestines that can self-renew and differentiate into many different types of cells that play important roles in maintaining a healthy gut. Abnormal gut stem cell differentiation can lead to serious gastrointestinal disease

肠道干细胞是肠道中的细胞，可以自我更新并分化成许多不同类型的细胞，在维持肠道健康方面发挥着重要作用。肠道干细胞分化异常可导致严重的胃肠道疾病