Characterizing the mechanisms by which apoptotic exosomes cargo specific sets of nucleic acids that shape endothelial function

表征凋亡外泌体携带塑造内皮功能的特定核酸组的机制

• 批准号: 486291
• 负责人: Lanoie Maude
• 金额: $ 1.27万
• 依托单位: Universit de Montral
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-12-01 至 2023-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=486291&lang=en
• 关键词: Apoptosis; Endothelial Function; Exosomes; Extracellular Vesicle; Ischemia-Reperfusion; Macropinocytosis; Microvasculature; Renal Transplantation

At the time of kidney transplantation, lack of blood supply can injure small vessels that provide oxygen and nutrients to the kidneys. The loss of these small blood vessels can lead to long-term kidney failure. Our group identified tiny fragments of vascu

肾移植时，血液供应不足会损伤为肾脏提供氧气和营养的小血管。这些小血管的丧失会导致长期肾衰竭。我们的小组发现了血管的微小碎片