Identifying differences in the intestinal microbiome between healthy, inflammatory bowel disease (IBD), and IBD-associated colorectal cancer, that mediate dietary fibre-associated inflammation

确定健康炎症性肠病 (IBD) 和 IBD 相关结直肠癌之间肠道微生物组的差异，这些差异介导膳食纤维相关炎症

• 批准号: 486052
• 负责人: Voisin Athalia S
• 金额: $ 1.27万
• 依托单位: University of Manitoba
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-12-01 至 2023-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=486052&lang=en
• 关键词: Colorectal Cancer; Crohn Disease; Diet; Dietary Fibre; Dysbiosis; Inflammation; Inflammatory Bowel Diseases; Microbiome; Ulcerative Colitis; ß­-Fructan

Incidence of the severe and chronic inflammatory bowel diseases (IBD) is increasing and yet the cause remains unknown. Diet and the gut microbiome (bacteria, fungi, and viruses) play a role. Specifically, dietary fibres are not digested; instead, they req

严重和慢性炎症性肠病（IBD）的发病率正在增加，但其原因仍不清楚。饮食和肠道微生物组（细菌、真菌和病毒）发挥着作用。具体来说，膳食纤维不被消化；相反，他们要求