Barriers to the transmission of multidrug-resistance conjugative plasmids of the IncC group: surface exclusion, entry exclusion and anti-restriction

IncC组多药耐药接合质粒传播的障碍：表面排斥、进入排斥和反限制

• 批准号: 467968
• 负责人: Burrus Vincent
• 金额: $ 58.24万
• 依托单位: Universit de Sherbrooke
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-09-01 至 2027-09-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=467968&lang=en
• 关键词: Antibiotic Resistance; Barriers To Dna Transfer; Conjugation; Conjugative Plasmids; Entry Exclusion; Horizontal Gene Transfer; Restriction-Modification; Salmonella Enterica; Surface Exclusion; Vibrio Cholerae

With the discovery and use of the first antibiotics during the 1930s, the mortality and morbidity associated with infectious diseases have considerably decreased. However, over the years, the usage, abuse and misuse of antibiotics have selected "superbugs

随着 20 世纪 30 年代第一种抗生素的发现和使用，与传染病相关的死亡率和发病率大幅下降。然而，多年来抗生素的使用、滥用和误用却选择了“超级细菌”