Spatio-temporal dynamics of immune and non-immune islet injury in Type 1 Diabetes

1 型糖尿病免疫和非免疫胰岛损伤的时空动态

• 批准号: 467723
• 负责人: Thompson Peter
• 金额: $ 127.49万
• 依托单位: University of Manitoba
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-08-01 至 2026-08-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=467723&lang=en
• 关键词: Beta Cell Heterogeneity; Human Pancreas Slices; Nonobese Diabetic (Nod) Mouse Model; Pancreatic Islet Beta Cells; Type 1 Diabetes

Type 1 diabetes (T1D) varies significantly from person to person in terms of time to onset, rate of progression and insulin use, but the reasons underlying these differences are not known. These knowledge gaps hamper the development of treatments that are

1 型糖尿病 (T1D) 在发病时间、进展速度和胰岛素使用方面因人而异，但造成这些差异的原因尚不清楚。这些知识差距阻碍了治疗方法的开发