Understanding the molecular processes governing phagocytic capacity and appetite, and phagosome resolution in macrophages

了解控制巨噬细胞吞噬能力和食欲以及吞噬体分辨率的分子过程

• 批准号: 461647
• 负责人: Botelho Roberto J
• 金额: $ 61.02万
• 依托单位: Toronto Metropolitan University
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-03-01 至 2027-03-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=461647&lang=en
• 关键词: Adaptation; Biophysical; Clathrin; Immunity; Infection; Lysosomes; Macrophages; Membranes; Phagocytosis; Phagosomes

Macrophages are a diverse group of immune cells that play a major role in eliminating dangerous particles like bacteria, pollutants, and even tumour and dead cells. Macrophages do this by recognizing, binding to, and then engulfing these particles - this

巨噬细胞是一组多样化的免疫细胞，在消除细菌、污染物、甚至肿瘤和死细胞等危险颗粒方面发挥着重要作用。巨噬细胞通过识别、结合然后吞噬这些颗粒来做到这一点——这