Comparative Transcriptional Profiling of Both Immortalized Human Lung Cells and Patient-Derived Lung Organoids Infected with Circulating SARS-CoV-2 Variants of Concern (VOCs)

感染循环 SARS-CoV-2 变异体 (VOC) 的永生化人肺细胞和患者来源的肺类器官的转录谱比较

• 批准号: 467019
• 负责人: Presley Lianne
• 金额: $ 1.27万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-12-01 至 2022-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=467019&lang=en
• 关键词: Host-Virus Interactions; Human Coronavirus 229e; Lung Organoid; Molecular Virology; Rna Sequencing; Sars-Cov-2 Variants Of Concern; Transcriptional Profiling

Like other viruses, SARS-CoV-2, the virus that causes COVID-19, constantly changes via mutation. Throughout the global pandemic, several variants of concern (VOCs) have been identified. A variant is of concern if it (1) spreads more easily, (2) is associa

像其他病毒一样，导致共证19的病毒SARS-COV-2通过突变不断变化。在整个全球大流行中，已经确定了几种关注的变体（VOC）。如果（1）更容易传播，则值得关注的是（2）是关联