Sources and Environmental Fate of Contaminants of Emerging Concern

新兴污染物的来源和环境归趋

基本信息

  • 批准号:
    RGPIN-2019-05761
  • 负责人:
  • 金额:
    $ 1.75万
  • 依托单位:
  • 依托单位国家:
    加拿大
  • 项目类别:
    Discovery Grants Program - Individual
  • 财政年份:
    2020
  • 资助国家:
    加拿大
  • 起止时间:
    2020-01-01 至 2021-12-31
  • 项目状态:
    已结题

项目摘要

Human activities release many anthropogenic chemicals to the natural environment. Some of these chemicals are produced and consumed with high volumes globally, may be persistent in the environment and pose risks to ecosystems and humans. Thus, the sources, pathways and environmental fate of anthropogenic chemicals are of significant scientific and public concern. In recent years, there has been increasing attention paid to the environmental behavior of contaminants of emerging concern (CECs) such as plastic additives, industrial byproducts, and personal care products. They may enter the environment during manufacture, application, and waste disposal processes. Many of these substances are potentially toxic to organisms and humans at low concentrations, but they are not commonly monitored and regulated. Substituted diphenylamine antioxidants (SDPAs), benzotriazole UV stabilizers (BZT-UVs), and polyhalogenated carbazoles (PHCZs) are three classes of chemicals that are present in many products such as plastics, rubbers, fuels, lubricants, dyes, food packages, and personal care products. These compounds are potentially persistent, bioaccumulative and toxic in the environment. However, our knowledge about the ecological risks of these contaminants is insufficient. To this end, this research program will investigate: (1) the sources and pathways of target CECs in the aquatic environment; (2) the biomagnification behavior of target CECs in aquatic food webs; and (3) the biotransformation processes of target CECs. This research will use the St. Lawrence River System as the study site. By understanding the sources, pathways, and environmental fate of these CECs, we can access the exposure risks of humans and organisms to these contaminants and develop rational approaches to protecting human and ecosystem health.
人类活动向自然环境释放许多人为化学物质。其中一些化学品在全球范围内大量生产和消费,可能在环境中持久存在,并对生态系统和人类构成风险。因此,人为化学物质的来源、途径和环境归趋受到科学界和公众的重大关注。近年来,人们越来越关注塑料添加剂、工业副产品和个人护理产品等新兴污染物(CEC)的环境行为。它们可能在制造、应用和废物处理过程中进入环境。其中许多物质在低浓度下对生物体和人类具有潜在毒性,但它们通常不受监控和监管。取代二苯胺抗氧化剂 (SDPA)、苯并三唑紫外线稳定剂 (BZT-UV) 和多卤咔唑 (PHCZ) 是三类化学品,存在于许多产品中,例如塑料、橡胶、燃料、润滑油、染料、食品包装和个人用品。护理产品。这些化合物在环境中具有潜在的持久性、生物累积性和毒性。然而,我们对这些污染物的生态风险的了解还不够。为此,本研究计划将调查:(1)水环境中目标CEC的来源和途径; (2)目标CEC在水生食物网中的生物放大行为; (3)目标CEC的生物转化过程。这项研究将使用圣劳伦斯河水系作为研究地点。通过了解这些 CEC 的来源、途径和环境归趋,我们可以了解人类和生物体对这些污染物的暴露风险,并制定合理的方法来保护人类和生态系统健康。

项目成果

期刊论文数量(0)
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科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Lu, Zhe其他文献

Coupling between voltage sensors and activation gate in voltage-gated K+ channels.
电压门控 K 通道中电压传感器和激活门之间的耦合。
  • DOI:
  • 发表时间:
    2002-11
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Lu, Zhe;Klem, Angela M;Ramu, Yajamana
  • 通讯作者:
    Ramu, Yajamana
Energetics of ångström-scale conformational changes in an RCK domain of the MthK K+ channel.
MthK K 通道 RCK 结构域中埃级构象变化的能量学。
  • DOI:
  • 发表时间:
    2019
  • 期刊:
  • 影响因子:
    16.8
  • 作者:
    Lewis, John H;Lu, Zhe
  • 通讯作者:
    Lu, Zhe
A Clinical Prediction Model for Patients with Acute Large Vessel Occlusion Due to Underlying Intracranial Atherosclerotic Stenosis
颅内动脉粥样硬化性狭窄导致急性大血管闭塞患者的临床预测模型
  • DOI:
    10.1007/s00062-022-01241-3
  • 发表时间:
    2023-06
  • 期刊:
  • 影响因子:
    2.8
  • 作者:
    Cai, Yusen;Gu, Yuting;Wang, Yanhong;Wang, Peng;Zhang, Lei;Liu, Chaolai;Chu, Jianfeng;Li, Hui;Lu, Zhe;Zhou, Yafei;Liu, Huakun
  • 通讯作者:
    Liu, Huakun
Assessing the Toxicity of Benzotriazole Ultraviolet Stabilizers to Fishes: Insights into Aryl Hydrocarbon Receptor-Mediated Effects
评估苯并三唑紫外线稳定剂对鱼类的毒性:深入了解芳基烃受体介导的影响
  • DOI:
    10.1021/acs.est.3c06117
  • 发表时间:
    2024-01-09
  • 期刊:
  • 影响因子:
    11.4
  • 作者:
    Johnson, Hunter M.;Dubiel, Justin;Collins, Cameron H.;Eriksson, Andreas N. M.;Lu, Zhe;Doering, Jon A.;Wiseman, Steve
  • 通讯作者:
    Wiseman, Steve
Removal of phospho-head groups of membrane lipids immobilizes voltage sensors of K+ channels.
去除膜脂的磷酸头基团可固定 K 通道的电压传感器。
  • DOI:
  • 发表时间:
    2008-02-14
  • 期刊:
  • 影响因子:
    64.8
  • 作者:
    Xu, Yanping;Ramu, Yajamana;Lu, Zhe
  • 通讯作者:
    Lu, Zhe

Lu, Zhe的其他文献

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{{ truncateString('Lu, Zhe', 18)}}的其他基金

Sources and Environmental Fate of Contaminants of Emerging Concern
新兴污染物的来源和环境归趋
  • 批准号:
    RGPIN-2019-05761
  • 财政年份:
    2022
  • 资助金额:
    $ 1.75万
  • 项目类别:
    Discovery Grants Program - Individual
Sources and Environmental Fate of Contaminants of Emerging Concern
新兴污染物的来源和环境归趋
  • 批准号:
    RGPIN-2019-05761
  • 财政年份:
    2022
  • 资助金额:
    $ 1.75万
  • 项目类别:
    Discovery Grants Program - Individual
Sources and Environmental Fate of Contaminants of Emerging Concern
新兴污染物的来源和环境归趋
  • 批准号:
    RGPIN-2019-05761
  • 财政年份:
    2021
  • 资助金额:
    $ 1.75万
  • 项目类别:
    Discovery Grants Program - Individual
Microplastics and plastic additives in the St. Lawrence River and Estuary: occurrence, fate and impacts
圣劳伦斯河和河口的微塑料和塑料添加剂:发生、归宿和影响
  • 批准号:
    558410-2020
  • 财政年份:
    2021
  • 资助金额:
    $ 1.75万
  • 项目类别:
    Alliance Grants
Microplastics and plastic additives in the St. Lawrence River and Estuary: occurrence, fate and impacts
圣劳伦斯河和河口的微塑料和塑料添加剂:发生、归宿和影响
  • 批准号:
    558410-2020
  • 财政年份:
    2021
  • 资助金额:
    $ 1.75万
  • 项目类别:
    Alliance Grants
Sources and Environmental Fate of Contaminants of Emerging Concern
新兴污染物的来源和环境归趋
  • 批准号:
    RGPIN-2019-05761
  • 财政年份:
    2021
  • 资助金额:
    $ 1.75万
  • 项目类别:
    Discovery Grants Program - Individual
Microplastics and plastic additives in the St. Lawrence River and Estuary: occurrence, fate and impacts
圣劳伦斯河和河口的微塑料和塑料添加剂:发生、归宿和影响
  • 批准号:
    558410-2020
  • 财政年份:
    2020
  • 资助金额:
    $ 1.75万
  • 项目类别:
    Alliance Grants
Microplastics and plastic additives in the St. Lawrence River and Estuary: occurrence, fate and impacts
圣劳伦斯河和河口的微塑料和塑料添加剂:发生、归宿和影响
  • 批准号:
    558410-2020
  • 财政年份:
    2020
  • 资助金额:
    $ 1.75万
  • 项目类别:
    Alliance Grants
Sources and Environmental Fate of Contaminants of Emerging Concern
新兴污染物的来源和环境归趋
  • 批准号:
    RGPIN-2019-05761
  • 财政年份:
    2019
  • 资助金额:
    $ 1.75万
  • 项目类别:
    Discovery Grants Program - Individual
Sources and Environmental Fate of Contaminants of Emerging Concern
新兴污染物的来源和环境归趋
  • 批准号:
    DGECR-2019-00268
  • 财政年份:
    2019
  • 资助金额:
    $ 1.75万
  • 项目类别:
    Discovery Launch Supplement

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  • 批准号:
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    $ 1.75万
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Sources and Environmental Fate of Contaminants of Emerging Concern
新兴污染物的来源和环境归趋
  • 批准号:
    RGPIN-2019-05761
  • 财政年份:
    2022
  • 资助金额:
    $ 1.75万
  • 项目类别:
    Discovery Grants Program - Individual
Sources and fate of plastic-associated contaminants in the environment- novel analysis strategies to evaluate human and environmental exposure
环境中塑料相关污染物的来源和归宿——评估人类和环境暴露的新颖分析策略
  • 批准号:
    RGPIN-2021-03770
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    2022
  • 资助金额:
    $ 1.75万
  • 项目类别:
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