Investigating molecular mechanisms controlling the developmental emergence and maintenance of adult neural stem cells.

研究控制成体神经干细胞发育出现和维持的分子机制。

• 批准号: 433859
• 负责人: Yuzwa Scott A
• 金额: $ 71.06万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-10-01 至 2025-10-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=433859&lang=en
• 关键词: Cell Signaling; Development; Extrinsic Regulation; Neural Stem Cells; Quiescence; Stroke

Neural stem cells (NSCs) are important for aspects of brain maintenance as well as for responding, in a limited manner, to brain injuries such as stroke. NSCs are largely dormant in nature in that they divide infrequently but are primed for activation to

神经干细胞（NSC）对于脑部维护方面以及以有限的方式对脑损伤（例如中风）的反应很重要。 NSC在很大程度上处于休眠状态，因为它们很少分裂，但被启动以激活为