Pyrrole Chemistry for Chemical Biology and Energy

化学生物学和能源领域的吡咯化学

• 批准号: CRC-2019-00014
• 负责人: Thompson, Alison
• 金额: $ 14.57万
• 依托单位: Dalhousie University
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=695179
• 关键词: Pyrrole; Chemistry; Chemical; Biology; Energy

Pyrrole is an attractive component of materials used in studying and treating disease and in the use of light to generate responses that report sensing or enable storage/delivery of energy. Dr. Thompson's research includes the development of sensors to monitor glucose levels in humans, of air-stable enzymes involved in biosynthesis and of materials for redox-flow batteries. It includes generating fundamental knowledge of (poly)pyrroles that emit light from the red into the infrared. Underpinning all of these is the development of practical syntheses of molecules incorporating pyrroles, syntheses which are robust, economical and tolerant of a wide variety of substituents.

吡咯是用于研究和治疗疾病以及利用光产生报告传感或实现能量存储/传递的反应的材料中有吸引力的成分。汤普森博士的研究包括开发监测人体葡萄糖水平的传感器、参与生物合成的空气稳定性酶以及氧化还原液流电池材料。它包括生成（聚）吡咯的基础知识，该化合物发射从红光到红外光的光。所有这些的基础是掺入吡咯的分子的实用合成的发展，这些合成是稳健的、经济的并且能够耐受多种取代基。