Replacing a supercontinuum ultrafast fiber laser with tunable outputs in the Visible and NIR and adding a UV source at 375 nm

用可见光和近红外可调输出取代超连续谱超快光纤激光器，并添加 375 nm 的紫外光源

• 批准号: RTI-2020-00235
• 负责人: Cosa, Gonzalo
• 金额: $ 10.62万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=693605
• 关键词: Replacing; supercontinuum; ultrafast; fiber; laser

This is an application for funds to replace a supercontinuum ultrafast fiber laser with pulsed (6ps fwhm), tunable (up to 8 simultaneous) outputs in the Visible and Near Infrared range of the spectrum, from 450 nm to 1,400 nm. The laser replaces one previously acquired with an NSERC RTI-1 award (2013 competition). The existing unit has failed beyond repair. A trade in of the broken unit has resulted in a 20% discount. We will also incorporate an additional unit with UV output (375 nm). The sources will be integrated to our combined setup for time correlated single photon counting (TCSPC, for ensemble time-resolved measurements) and fluorescence lifetime imaging (FLIM).******The TCSPC-FLIM setup is the sole turn-key instrument currently available in our department (and to our knowledge on campus) capable of acquiring ensemble emission lifetimes and anisotropy lifetimes. The instrument is used by multiple groups in our department including the applicant, three co-applicants but also and on a regular basis, eight other colleagues within chemistry, and additional colleagues in Chemical Engineering, Bioengineering, Biomedical Engineering, etc. It is further the only equipment of its kind in Montreal, optimized for ensemble lifetime studies, fluorescence lifetime imaging studies and associated single molecule lifetime studies.******The supercontinuum laser source used in our TCSCP and FLIM setup was repaired last December 2018 ($12K cost) and broke shortly after with no possibility to further repair it. The requested Visible-Near Infrared excitation source to replace the broken one, and the addition of a UV source, will enable users to conduct experiments on a wide range of luminescent molecules and nanoparticles/materials whose absorption and emission extends from the UV to the Visible and the Near Infrared range of the electromagnetic spectrum from 375 nm to 1,400 nm. The requested pulsed supercontinuum and UV sources will continue empowering a whole new dimension of experiments critical to our research efforts and those of colleagues, enabling studies such as single molecule fluorescence lifetime, lifetime imaging of cells and materials, ensemble fluorescence lifetime and ensemble anisotropy lifetime experiments among others. ******The setup is physically located in the Department of Chemistry at McGill University. Replacing the supercontinuum ultrafast fiber laser with tunable outputs is absolutely essential to the research of the applicant and colleagues at McGill and elsewhere. In respect to the regular users, the instrument supports research programs in semiconductor quantum dots, biomaterials, nanomaterials for fluorescence upconversion, novel sensors and reporters, biophysical studies on protein-DNA interactions, research into free radical sensors, and cell imaging, among others.**

这是用于用脉冲（6PS FWHM），可调（最多8个同时）输出的超级超快纤维激光器的资金应用程序，可在可见光和接近红外范围内的频谱范围从450 nm到1,400 nm。激光取代了先前获得的NSERC RTI-1奖（2013年比赛）。现有单位无法维修。破碎单位的交易导致了20％的折扣。我们还将合并一个具有UV输出（375 nm）的额外单元。 The sources will be integrated to our combined setup for time correlated single photon counting (TCSPC, for ensemble time-resolved measurements) and fluorescence lifetime imaging (FLIM).******The TCSPC-FLIM setup is the sole turn-key instrument currently available in our department (and to our knowledge on campus) capable of acquiring ensemble emission lifetimes and anisotropy lifetimes.该仪器在我们部门的多个小组中使用，包括申请人，三名共同申请人，以及定期的，化学中的其他八个同事以及化学工程，生物工程，生物医学工程等的其他同事。它是蒙特利亚中唯一的设备，用于蒙特利亚的唯一设备，对集合的生命研究，荧光生活和相关的单个研究完善了整体研究，该研究均可进行研究。我们的TCSCP和FLIM设置中使用的激光源于2018年12月进行了维修（成本为12,000美元），不久之后就破产了，无需进一步维修。所需的可见新红外线激发源代替了破碎的激发源，并添加紫外线源将使用户能够对各种发光分子和纳米颗粒/材料进行实验，这些分子和纳米颗粒/材料的吸收和排放范围从紫外线延伸到可见的，并近乎可见的和近乎电子范围的电子磁场范围。所需的脉冲超大胆和紫外线源将继续增强对我们的研究工作至关重要的全新实验维度，从而使单分子荧光寿命，细胞和材料的寿命成像，集合荧光生命周期和集合各向异性植物生命周期的实验等研究促进了研究。 ******该设置物理位于麦吉尔大学化学系。用可调输出代替超局部超快纤维激光器对于麦吉尔和其他地方的申请人和同事的研究绝对必不可少。关于常规用户，该仪器支持半导体量子点，生物材料，用于荧光上转换的纳米材料，新型传感器和记者的纳米材料，蛋白质-DNA相互作用的生物物理研究，对自由基传感器的研究，以及细胞成像的研究。