Post-transcriptional control of Sox9 during endocrine pancreas development: role of microRNAs

内分泌胰腺发育过程中 Sox9 的转录后控制：microRNA 的作用

• 批准号: 190644
• 负责人: Lynn Francis C
• 金额: $ 43.21万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-09-01 至 2014-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=190644&lang=en
• 关键词: Development; Diabetes; Human Embryonic Stem Cells; Microrna; Sox9; Transcription Factor

To date, the only successful approach for curing insulin-dependent diabetes is to replace the insulin-producing ß-cells that have been destroyed by disease. Pancreas and islet cell transplantation are promising therapeutic strategies; however, scarcity of

迄今为止，治疗胰岛素依赖型糖尿病的唯一成功方法是替换已被疾病破坏的产生胰岛素的β细胞，并且胰岛细胞移植是有前途的治疗策略。