Development of a Portable, Continuous, and Real-time Muscle Metabolism Monitoring System Based On Near-Infrared Spectroscopy Analysis and Mobile Edge Computing

基于近红外光谱分析和移动边缘计算的便携式、连续、实时肌肉代谢监测系统的开发

• 批准号: 522719-2017
• 负责人: Cai, Jun
• 金额: $ 2.22万
• 依托单位: University of Manitoba
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=683716
• 关键词: Development; Portable; Continuous; Real; time

Non-communicable chronic diseases (NCDs), such as diabetes, have been a leading cause of morbidity, mortality and health care expenditures in most developed countries including Canada, and appear to be on the rise. The pivotal role of physical activity in improving NCD patients' rehabilitation has been widely recognized, which requests thorough understanding of muscle oxygenation. Recently, technology based on near-infrared spectroscopy (NIRS) has been proposed as a promising way to investigate muscle metabolism because of its noninvasive and portable nature. Although it is promising, applying NIRS technology for muscle metabolism measurement is challenging due to the complex profiles of noise, interference, and distortion to the received signal, and the high computational complexity resulting from the application of advanced signal processing techniques. All these challenges have prevented industrial companies from developing commercial muscle metabolism monitors based on the NIRS technology.To well address all aforementioned challenges, this project will focus on developing a new implementation platform through integrating the state of art technologies in signal processing and mobile communications. Specifically, with meaningful industrial and academic collaborations, this work will develop 1) a new specified software platform for quantitative muscle oxygenation saturation (SmO2) measurement over a newly fabricated near-infrared sensor; and 2) novel protocols and algorithms addressing the adoption of mobile edge computing for real-time monitoring. This cutting-edge research will generate new ideas and knowledge in NIRS analysis and mobile edge computing, and, through collaborations, enable the development of new commercial products that will foster a vital competitive edge for Canadian healthcare industry in the international market place.

在包括加拿大在内的大多数发达国家，糖尿病等非通讯慢性病（NCD）一直是发病，死亡率和医疗保健支出的主要原因，并且似乎正在上升。体育活动在改善NCD患者康复中的关键作用已被广泛认可，这要求对肌肉氧合彻底了解。最近，由于其无创和便携性的性质，基于近红外光谱（NIR）的技术是研究肌肉代谢的一种有希望的方法。尽管这很有希望，但由于噪声，干扰和对接收信号的扭曲的复杂曲线，以及由于应用高级信号处理技术而产生的高计算复杂性，将NIRS技术应用于肌肉代谢测量很具有挑战性。 所有这些挑战都阻止了工业公司基于NIRS技术开发商业肌肉代谢监测器。为了很好地应对上述所有挑战，该项目将专注于通过将艺术技术在信号处理和移动通信中整合到新的实施平台上。具体而言，通过有意义的工业和学术合作，这项工作将开发一个新的指定软件平台，用于定量肌肉氧合饱和度（SMO2）测量，对新近制造的近红外传感器进行测量； 2）用于实时监视的移动边缘计算采用的新颖协议和算法。这项尖端的研究将在NIRS分析和移动边缘计算中产生新的想法和知识，并通过合作，可以开发新的商业产品，从而为国际市场上的加拿大医疗保健行业培养至关重要的竞争优势。