Understanding the activation and the roles of the IKK complex-NF-kappaB signaling cascade in the inflammatory and hypertrophic actions of Angiotensin II in vitro and in vivo

了解 IKK 复合物-NF-kappaB 信号级联在体外和体内血管紧张素 II 炎症和肥大作用中的激活和作用

• 批准号: 170939
• 负责人: Servant Marc
• 金额: $ 43.28万
• 依托单位: Universit de Montral
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-09-01 至 2013-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=170939&lang=en
• 关键词: Angiotensin Ii; Atherosclerosis; Chromatin; Hypertension; Kinases; Signal Transduction

Cardiovascular disease (CVD), including heart disease, stroke and peripheral vascular disease, is the leading cause of death in Canada and in Western society. When death is not the end point, CVD jeopardized the quality of life. CVD is also the leading ca

心血管疾病（CVD），包括心脏病，中风和周围血管疾病，是加拿大和西方社会死亡的主要原因。当死亡不是终点时，CVD危害了生活质量。 CVD也是领先的CA