CRISPR-Cas9 targeting of secretory pathway furin in human cells: Insights into the biological roles of furin in the flaviviral lifecycle.

CRISPR-Cas9 靶向人类细胞中的分泌途径弗林蛋白酶：深入了解弗林蛋白酶在黄病毒生命周期中的生物学作用。

• 批准号: 406422
• 负责人: Chan Carly C
• 金额: $ 1.27万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-12-01 至 2019-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=406422&lang=en
• 关键词: 2d Cell Culture And 3d Brain Organoid Models; Cell Toxicity And Antiviral Effects; Crispr-Cas9 Gene Editing; Flaviviruses (Dengue; Host Factor Knockouts; Host Factors In Viral Life Cycles; Host Secretory Pathway Furin; Human Pluripotent Stem Cell-Derived

CRISPR-Cas9 targeting of secretory pathway furin in human cells: Insights into the biological roles of furin in the flaviviral lifecycle. There is currently a lack of therapeutic options to treat neurotropic viral diseases caused by flaviviruses like De

CRISPR-Cas9 靶向人类细胞中的分泌途径弗林蛋白酶：深入了解弗林蛋白酶在黄病毒生命周期中的生物学作用。 目前缺乏治疗由 De 等黄病毒引起的神经性病毒性疾病的治疗选择