The role of mesenchymal tissues in the establishment of the blastema and their contribution to mammalian digit tip regeneration

间充质组织在胚基形成中的作用及其对哺乳动物指尖再生的贡献

• 批准号: 397368
• 负责人: Storer Mekayla A
• 金额: $ 9.83万
• 依托单位: Hospital for Sick Children (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-11-01 至 2021-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=397368&lang=en
• 关键词: Blastema; Dedifferentiation; Growth Factors; Ligand - Receptor Modelling; Lineage Tracing; Mammalian Tissue Regeneration; Mesenchymal Cells; Mesenchymal Precursor Cells; Single Cell Rna Sequencing; Transcriptomics

Some animals, such as newts and lizards display a remarkable ability to regenerate parts of their body. In mammals, however, this ability has been lost, with one exception; in both mice and humans, true multi-tissue regeneration occurs when you injure you

一些动物，例如蝾螈和蜥蜴，表现出非凡的身体部位再生能力。然而，在哺乳动物中，这种能力已经丧失，只有一个例外：在小鼠和人类中，当您受伤时，就会发生真正的多组织再生