ROS metabolism and mitochondrial function in the aging process and in age-dependent diseases.

衰老过程和年龄依赖性疾病中的活性氧代谢和线粒体功能。

• 批准号: 368962
• 负责人: Hekimi Siegfried
• 金额: $ 222.05万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-09-01 至 2024-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=368962&lang=en
• 关键词: Aging; Apoptotic And Ras Signaling Pathways; Caenorhabditis Elegans; Inducible Conditional Transgenic Mouse Models; Mitochondria; Parkinson'S Disease; Reactive Oxygen (Ros) And Nitrogen Species (Rns); Superoxide Dismutases And Nitric Oxide Synthases; Ubiq

Most diseases that threaten Canadians, including cancer, heart disease, metabolic diseases, and neurodegenerative disease (such as Alzheimer's disease and Parkinson's disease) are associated with age: they are much more likely in older individuals. Our g

威胁加拿大人的大多数疾病，包括癌症，心脏病，代谢疾病和神经退行性疾病（例如阿尔茨海默氏病和帕金森氏病）与年龄有关：它们在老年人中的可能性更大。 我们的g