Multi-beam X-ray Source based Computed Tomography Platform

基于多束X射线源的计算机断层扫描平台

• 批准号: RTI-2017-00109
• 负责人: Yeow, Tzewei
• 金额: $ 10.75万
• 依托单位: University of Waterloo
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=616556
• 关键词: Multi; beam; ray; Source; based

Advances in computed tomography (CT) imaging technology are currently limited by the low number of X-ray generators present on a single CT machine. Currently, X-ray tube is mechanically rotated around a patient to acquire images from multiple angles - this approach only allows for limited resolution of images, leas to excessive radiation exposure to the patient, and is time consuming. The availability of a multi-beam X-ray CT will greatly improve imaging resolution and imaging speed, while decreasing radiation dosage delivered to patients. Recently, Dr. Yeow has made significant research progress on dual-beam X-ray sources, which has laid the foundation for realization of a functional multi-beam X-ray CT. However, the existing experimental setup has exceeded its maximum working capacity, and an X-ray testing platform with a higher power range is necessary to fully characterize device performance such as X-ray power, switching speed, and lifetime. We propose funding for an X-ray system to be used for the development and optimization of next generation X-ray imaging systems. The proposed equipment is a second-hand real-time industrial X-ray system, which will be upgraded with Dr. Yeow’s new multi-beam X-ray sources technology and modified with Dr. Willett’s mechanical components. These components will allow the system to accommodate different radiation device designs, making it suitable for use in a range of experiments from medical imaging to industrial non-destructive testing (NDT). The aims of the program are to develop :(i) a novel carbon nanotube (CNT)-based field emission X-ray source, which will be used by Dr. Yeow in the development of a Fluence Field Modulated Computed Tomography (FFMCT) system for medical imaging; (ii) a field emission backscattering X-ray NDT system for spacecraft inspection; and (iii) nanomaterial-based X-ray dosimeter. The research program enabled by the proposed equipment will greatly enhance performance of Dr. Yeow’s multi-beam X-ray source and allow the development of a functional multi-beam X-ray CT. The proposed facility will also provide Dr. Wong the capability to capture 3D images that will be used in the development of 3D image reconstruction algorithms and software of the next generation CT; and will enable Dr. Willett’s crucial real-time NDT imaging of bone and bone-inspired composite materials to investigate multi-scale deformation phenomena during mechanical testing. The requested equipment will enable multi-beam X-ray CT, which will impact (i) health care systems, by providing better diagnostic capability to detect diseases such as cancer; and (ii) the manufacturing industry, by enabling fast, high-resolution NDT of materials and products. The requested equipment will also allow over ten graduate students and many co-op students to be trained in the fields of nanotechnology, biomedical engineering, medical imaging, and material research.

目前，计算机断层扫描（CT）成像技术的进步受到单个CT机器上存在的X射线发电机数量少的限制。当前，X射线管机械地围绕患者旋转以从多个角度获取图像 - 此方法仅允许图像的分辨率有限，借给患者过多的辐射暴露，并且耗时。多光束X射线CT的可用性将大大提高成像分辨率和成像速度，同时降低给患者的辐射剂量。最近，Yeow博士在双光束X射线源方面取得了重大的研究进展，该来源为实现功能性多光束X射线CT的基础奠定了基础。但是，现有的实验设置已超过其最大工作能力，并且必须具有更高功率范围的X射线测试平台，以完全表征设备性能，例如X射线功率，开关速度和寿命。 我们建议用于用于开发和优化下一代X射线成像系统的X射线系统的资金。拟议的设备是一种二手实时工业X射线系统，该系统将通过Yeow博士的新型多光束X射线源技术进行升级，并通过Willett博士的机械组件进行了修改。这些组件将允许系统适应不同的辐射设备设计，使其适合于从医学成像到工业非破坏性测试（NDT）的一系列实验。 该程序的目的是开发：（i）一种基于基于碳纳米管（CNT）的新型碳纳米管（CNT）田间发射X射线源，Yeow博士将用于医学成像的通用场调制计算机断层扫描（FFMCT）系统的开发； （ii）用于航天器检查的场发射反向散射X射线NDT系统； （iii）基于纳米材料的X射线剂量仪。由拟议的设备启用的研究计划将大大提高Yeow博士多光束X射线源的性能，并允许开发功能性的多光束X射线CT。拟议的设施还将为Wong博士提供捕获3D图像的能力，这些图像将用于开发下一代CT的3D图像重建算法和软件；并将使威利特博士对骨和骨骼启发的复合材料进行关键的实时NDT成像，以研究机械测试期间的多尺度变形现象。 请求的设备将通过提供更好的诊断能力来检测癌症等疾病，从而使多光束X射线CT能够影响（i）医疗保健系统； （ii）制造业，通过启用材料和产品的快速，高分辨率的NDT。要求的设备还将允许十多名研究生和许多合作社在纳米技术，生物医学工程，医学成像和物质研究领域接受培训。