Investigations on 4-hydroxy-2-alkylquinoline (HAQ) derivatives produced by Pseudomonas aeruginosa and Burkholderia species.

对铜绿假单胞菌和伯克霍尔德氏菌产生的 4-羟基-2-烷基喹啉 (HAQ) 衍生物的研究。

• 批准号: 181892
• 负责人: Deziel Eric
• 金额: $ 53.26万
• 依托单位: INRS - (Qubec, QC)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-03-01 至 2014-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=181892&lang=en
• 关键词: Antibiotic Resistance / Alternative Anti-Infective Drugs; Biowarfare Agent / Melioidosis; Cell-To-Cell Communication (Quorum Sensing) /Gene Regulation; Cystic Fibrosis; Functional Genomic / Genetic / Whole-Genome Transcriptome; Immunomodulatory Activity

Pseudomonas aeruginosa is a prevalent opportunistic human pathogen. Individuals who are immunocompromised or have breaches in normal barriers are especially susceptible to P. aeruginosa infections, such as cancer patients, those with indwelling medical de

铜绿假单胞菌是一种常见的机会性人类病原体。免疫功能低下或正常屏障遭到破坏的个体特别容易受到铜绿假单胞菌感染，例如癌症患者、留置医疗设备的患者