"Design, Calibration, and Inversion Algorithms for Novel Microwave Tomography Systems"

“新型微波断层扫描系统的设计、校准和反演算法”

• 批准号: 121454-2012
• 负责人: LoVetri, Joe
• 金额: $ 2.4万
• 依托单位: University of Manitoba
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=593310
• 关键词: Design; Calibration; Inversion; Algorithms; Novel

The main research goal of this proposed research program is to improve the performance of Microwave Tomography (MWT) systems for biomedical imaging applications. MWT uses microwave measurements to create a quantitative image of the bulk-electrical material properties of an object-of-interest (OI); typically the complex permittivity of the OI. In biomedical applications the OIs are typically in situ regions of the human body and the goal is to use the constructed complex permittivity maps to identify abnormal or diseased tissue in that region, e.g., the imaging and detection of cancerous tissue. The unique advantage of MWT for biomedical diagnostic imaging is that the reconstructed permittivity map is not directly imaged in any other modality and therefore contains unique and complementary information upon which to base a diagnosis. For biomedical applications, the greatest performance issue with current state-of-the-art MWT systems is the limited spatial resolution compared to other imaging modalities such as CT and MRI. In order to be a viable modality the achievable resolution of MWT must be increased while retaining the accuracy of the reconstructed complex permittivity maps. To achieve this goal the proposed research will investigation the three main aspects of MWT: a) the inversion algorithms used to create the images from appropriately calibrated scattered field data, b) the calibration techniques which take raw measurements from the MWT systems and produce appropriate data for the inversion algorithms, and c) the MWT system set-ups themselves which affect the electromagnetic (EM) model which must be used as well as the calibration procedure. These three aspects of MWT are interrelated, in sometimes subtle ways, and it is a fundamental thesis of this proposed research that a substantial enhancement of current MWT imaging performance can only be accomplished via the joint study of these three aspects.

该提出的研究计划的主要研究目标是改善用于生物医学成像应用的微波断层扫描（MWT）系统的性能。 MWT使用微波测量值来创建利益对象（OI）的整体电源材料特性的定量图像；通常是OI的复杂介电常数。在生物医学应用中，OI通常是人体的原位区域，目标是使用构造的复杂介电常数图来识别该地区的异常或患病组织，例如癌组织的成像和检测。 MWT对于生物医学诊断成像的独特优势是，重建的介电常数图并未直接成像任何其他方式，因此包含以诊断为基础的独特和互补信息。对于生物医学应用，与其他成像方式（例如CT和MRI）相比，当前最新MWT系统的最大性能问题是有限的空间分辨率。为了成为可行的方式，必须在保留重建的复杂介电常数图的准确性的同时增加MWT的可实现分辨率。 To achieve this goal the proposed research will investigation the three main aspects of MWT: a) the inversion algorithms used to create the images from appropriately calibrated scattered field data, b) the calibration techniques which take raw measurements from the MWT systems and produce appropriate data for the inversion algorithms, and c) the MWT system set-ups themselves which affect the electromagnetic (EM) model which must be used as well as the校准程序。 MWT的这三个方面有时以微妙的方式相互关联，这是这项提出的研究的基本论点，即仅通过对这三个方面的共同研究来实现当前MWT成像性能的实质性增强。