Polyelectrolyte Transport in Nanoporous Matrices

纳米多孔基质中的聚电解质传输

• 批准号: 418641-2012
• 负责人: Nazemifard, Neda
• 金额: $ 1.75万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=573760
• 关键词: Polyelectrolyte; Transport; Nanoporous; Matrices

From the fractionation of nanolitre DNA samples in micro devices to the injection of synthetic polymers into giant oil reservoirs, polyelectrolyte transport through nanoporous matrices is present in a wide range of length scales and a variety of chemical processes. Polyelectrolytes are polymers whose repeating units bear several charges in aqueous environments. Many biological molecules such as polypeptides (proteins) and DNA are polyelectrolytes. Synthesized polyelectrolytes are used in a wide range of technological and industrial fields such as enhanced oil recovery. However, most of the prior work on polyelectrolyte transport through nanoporous matrices has been done under simple and specific experimental conditions with few components, and thus lacks practical complexities. The proposed research program focuses on understanding polyelectrolyte migration mechanisms and quantifying transport parameters such as mobility, diffusion, and dispersion under a wide range of operational conditions using different experimental and numerical techniques. The objectives of the proposed research are: i) to develop, design, and fabricate micro/nanofluidic devices as an experimental platform to study polyelectrolyte transport with a focus on exploring designs and materials that can endure hostile operational conditions present in most energy production related processes, and ii) to extract and develop generalized functions and non-dimensional parameters to predict and subsequently control the mobility and dispersion of polyelectrolytes under different operational conditions. The significance of this research is that by using generalized functions to predict polyelectrolyte transport kinetics in nanoporous matrices, one can readily optimize the polyelectrolyte architecture and operating parameters such as force fields, matrix structure, and media properties to achieve high operational efficiencies without conducting numerous costly exploratory experiments. The research outcome will have direct impact in biotechnology and petroleum industry.

从微设备中纳米列列特尔DNA样品的分馏到将合成聚合物注射到巨大的油基储存中，通过纳米孔矩阵传输的聚电解质转运的长度范围很大，并且各种化学过程。聚电解质是聚合物，其重复单元在水性环境中带有多个电荷。许多生物分子，例如多肽（蛋白质）和DNA都是聚电解质。合成的聚电解质用于广泛的技术和工业领域，例如增强的石油回收。但是，在简单而特定的实验条件下，大多数关于通过纳米孔矩阵传输的关于聚电解质传输的工作的大多数工作，因此缺乏实际的复杂性。拟议的研究计划着重于理解聚电解质迁移机制，并使用不同的实验和数值技术在广泛的操作条件下量化运输参数，例如移动性，扩散和分散。 The objectives of the proposed research are: i) to develop, design, and fabricate micro/nanofluidic devices as an experimental platform to study polyelectrolyte transport with a focus on exploring designs and materials that can endure hostile operational conditions present in most energy production related processes, and ii) to extract and develop generalized functions and non-dimensional parameters to predict and subsequently control the mobility and dispersion of polyelectrolytes under different操作条件。 这项研究的意义在于，通过使用广义功能来预测纳米多孔矩阵中的聚电解质传输动力学，人们可以很容易地优化聚电解质体系结构和操作参数，例如力场，矩阵结构和媒体属性，以实现高功能，而无需进行大量成本的探索性探索性探索性实验。研究结果将直接影响生物技术和石油行业。