Slime Wars: Developing inhibitors against bacterial biofilms

史莱姆战争：开发针对细菌生物膜的抑制剂

• 批准号: 296849
• 负责人: Baker Perrin
• 金额: $ 10.2万
• 依托单位: Hospital for Sick Children (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-10-01 至 2015-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=296849&lang=en
• 关键词: Antibiotic Resistance; Biofilm Development; Enzyme Characterization; Exopolysaccharide Biosynthesis; Infection; Pseudomonas Aeruginosa; Small Molecule Inhibitors; X-Ray Crystallography

An estimated 80% of all bacterial infections are biofilm related. Biofilms are communities of bacteria that grow on surfaces. These bacterial cities encapsulate themselves in a slime "force-field" composed of chains of sugars molecules to protect themselv

估计所有细菌感染的80％与生物膜有关。生物膜是在表面上生长的细菌群落。这些细菌城市将自己封装在由糖分子链组成的粘液“力场”中，以保护它们