Natural abundance compound specific isotope analysis of lipids: tracing anthropogenic impacts and responses

脂质的天然丰度化合物特异性同位素分析：追踪人为影响和反应

• 批准号: 288309-2009
• 负责人: Slater, Gregory
• 金额: $ 2.19万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=525779
• 关键词: Natural; abundance; compound; specific; isotope

Scientific investigations of the sources, cycling and fates of organic compounds in the environment are a crucial component of a wide range of interdisciplinary research questions that are the forefront of current research into the interactions between human society and our environment. These research questions span a wide range from: i) understanding microbial roles in controlling the persistence, impacts and remediation of organic contaminants on human and ecosystem health in the fields of environmental geochemistry, contaminant hydrogeology, microbiology and bioremediation; to ii) understanding the fundamental role played by microbial communities in global biogeochemical cycles and their influence in geological weathering, biogeochemical nutrient cycling and climate change; to iii) understanding human responses and development as they interact with their environment by new research combining scientific approaches in geochemistry with archeology to elucidate human development. My research has played a leading role in developing new approaches in Compound Specific Isotope Analysis (CSIA), and in particular has identified that CSIA of lipids can be applied to a wide range of questions concerning human impacts on our environment that may negatively effect human and ecosystem health, as well as providing unique insights into the archeological record of human responses to our environment. This proposal will apply CSIA lipids to the range of topics listed above to contribute to our understanding of each of these topics and as such adding to the overall understanding of human interactions with our environment such that we can plan for the future by understanding the microbial processes and their potential fundamental role in crucial environmental questions concerning impacts and remediation of contaminants and climate change, and by understanding the geoarcheological record of human responses to environmental change to contribute to our ability tot predict our future responses.

环境中有机化合物的来源，骑自行车和命运的科学研究是广泛的跨学科研究问题的关键组成部分，这是当前对人类社会与我们环境之间相互作用的研究的最前沿。 这些研究问题范围很广，i）了解微生物在控制环境地球化学，污染物水性地质学，微生物学和生物修复领域对有机污染物对人类和生态系统健康的持久性，影响和补救方面的微生物作用； ii）了解微生物群落在全球生物地球化学循环中所起的基本作用及其在地质风化，生物地球化学营养循环和气候变化中的影响； iii）了解人类的反应和发展与环境相互作用，通过将地球化学中的科学方法与考古学相结合以阐明人类发展的新研究。 我的研究在开发复合特异性同位素分析（CSIA）的新方法方面发挥了领先作用，尤其是确定脂质的CSIA可以应用于有关人类对我们环境的影响的广泛问题，这些问题可能对人类和生态系统的健康产生负面影响，并为人类对我们环境的考古记录提供独特的见解。 该提案将将CSIA脂质应用于上面列出的一系列主题，以帮助我们理解这些主题，从而增加对人类与环境的互动的总体理解，以便我们可以通过理解微生物过程及其潜在的基本角色来计划未来，从而在对环境中的重要影响以及对环境的影响以及对环境的影响以及对环境的影响，以及对环境的影响，以及对环境的影响，以及对环境的回应，并响应着零件的变化，并构成了环境的变化，并且会发生变化的环境变化，并将其探讨。促进我们的能力预测我们未来的回应。