The effect of a hybrid and injectible Nanoparticle BMP Delivery System on Bone Regeneration during Distraction Osteogenesis

混合注射纳米颗粒 BMP 输送系统对牵引成骨过程中骨再生的影响

• 批准号: 252462
• 负责人: Hamdy Reggie C
• 金额: $ 32.97万
• 依托单位: Research Institute of the McGill University Health Centre
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-03-01 至 2015-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=252462&lang=en
• 关键词: Bone Consolidation; Bone Morphogenetic Proteins; Distraction Osteogenesis; External Fixator; Gene Silencing; Immunohistochemistry; Microct; Mouse Model; Nanoparticle Delivery System; Quantum Dots

Distraction osteogenesis (DO) is a surgical technique used to treat limb length discrepancies, deformities and bone loss secondary to trauma, infection and tumours. DO involves performing an osteotomy and gradually distracting the two bone segments with a

牵引成骨 (DO) 是一种手术技术，用于治疗创伤、感染和肿瘤继发的肢体长度差异、畸形和骨质流失。 DO 包括进行截骨术，并用力逐渐分散两个骨段的注意力。