Diversity Oriented Clicking - Streamlined Synthesis of Molecular Frameworks

面向多样性的点击——分子框架的简化合成

• 批准号: DE240100449
• 负责人: Dr Christopher Smedley
• 金额: $ 29.54万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2024
• 资助国家: 澳大利亚
• 起止时间: 2024-01-01 至 2026-12-31
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE240100449
• 关键词: Diversity; Oriented; Clicking; Streamlined; Synthesis

Innovation in synthetic chemistry drives the discovery of new life-changing drugs, agrochemicals and functional materials. This project aims to use a novel chemical concept, termed Diversity Oriented Clicking, for new sustainable and streamlined synthetic transformations. The new chemical processes are expected to deliver improved economy, efficiency and precision in the synthesis of bioactive molecules and functional materials that are inaccessible or challenging to prepare with existing technologies. The conceptual and practical outcomes of this project are expected to benefit both academia and industry as the synthetic routes to diverse complex molecules can be greatly streamlined, and reducing chemical waste and required purification.

合成化学的创新推动了改变生命的新药物、农用化学品和功能材料的发现。该项目旨在使用一种新颖的化学概念，称为“面向多样性的点击”，以实现新的可持续和简化的合成转化。新的化学工艺预计将提高合成生物活性分子和功能材料的经济性、效率和精度，而这些是现有技术无法实现或难以制备的。该项目的概念和实际成果预计将使学术界和工业界受益，因为可以大大简化各种复杂分子的合成路线，并减少化学废物和所需的纯化。