Diversity Oriented Clicking - Streamlined Synthesis of Molecular Frameworks

面向多样性的点击——分子框架的简化合成

• 批准号: DE240100449
• 负责人: Dr Christopher Smedley
• 金额: $ 29.54万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2024
• 资助国家: 澳大利亚
• 起止时间: 2024-01-01 至 2026-12-31
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE240100449
• 关键词: Diversity; Oriented; Clicking; Streamlined; Synthesis

Innovation in synthetic chemistry drives the discovery of new life-changing drugs, agrochemicals and functional materials. This project aims to use a novel chemical concept, termed Diversity Oriented Clicking, for new sustainable and streamlined synthetic transformations. The new chemical processes are expected to deliver improved economy, efficiency and precision in the synthesis of bioactive molecules and functional materials that are inaccessible or challenging to prepare with existing technologies. The conceptual and practical outcomes of this project are expected to benefit both academia and industry as the synthetic routes to diverse complex molecules can be greatly streamlined, and reducing chemical waste and required purification.

合成化学的创新推动了新的改变生活的药物，农业化学和功能材料的发现。该项目旨在使用一种新型的化学概念，称为以多样性为导向的点击，进行新的可持续和简化的合成转换。预计新的化学过程将在合成生物活性分子和功能材料的合成中提高经济，效率和精度，这些分子和功能材料无法访问或具有挑战性，无法准备使用现有技术。预计该项目的概念和实际成果将受益于学术界和工业，因为可以极大地精简到各种复杂分子的合成途径，并减少化学废物和所需的纯化。