How does the brain process conflicting information?

大脑如何处理相互矛盾的信息？

• 批准号: DE240100614
• 负责人: Dr Belinda Lay
• 金额: $ 30.7万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2024
• 资助国家: 澳大利亚
• 起止时间: 2024-01-01 至 2026-12-31
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE240100614
• 关键词: How; does; brain; process; conflicting

Learning is the means by which we adapt to our environments. Occasionally, what we learn contradicts our present knowledge about the world. When this occurs, the old and new (contradictory) information compete for control over behaviour. Yet, how the brain processes contradictory information and resolves this competition is poorly understood. This project uses modern genetic tools in rodents to examine how the brain encodes and retrieves contradictory information to influence behaviour. The outcomes include new insights regarding the neural basis of adaptive behaviour; and the benefits include an understanding of why we sometimes fail to adapt to change, and disorders characterized by such failures (e.g., anxiety disorders, addiction).

学习是我们适应环境的手段。有时，我们学到的知识与我们对世界的当前知识相矛盾。发生这种情况时，新旧的（矛盾的）信息将争夺对行为的控制。但是，大脑如何处理矛盾的信息并解决这一竞争的理解很少。该项目使用啮齿动物中的现代遗传工具来检查大脑如何编码和检索矛盾的信息以影响行为。结果包括有关适应性行为神经基础的新见解；好处包括了解为什么我们有时无法适应变化，以及以这种失败为特征的疾病（例如焦虑症，成瘾）。