THE EFFECT OF LONG ACTING BRONCHODILATORS ON VENTILATION IN COPD

长效支气管扩张剂对 COPD 通气的影响

• 批准号: nhmrc : 1075330
• 负责人: Dr Stephen Milne
• 金额: $ 9.58万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/effect-long-acting-ventilation-copd/455664
• 关键词: EFFECT; LONG; ACTING; BRONCHODILATORS; VENTILATION

COPD is a common and important smoking-related lung disease. Well-established treatments with inhaled medications including long-acting bronchodilators have a proven clinical track record. However the physiological basis for their effects is still under investigation. This research examines some of the physiological changes in lung function and the response to long-acting bronchodilators in patients with COPD, and may help explain why some patients respond to therapy while others do not, leading to more targeted therapeutics

慢性阻塞性肺病是一种常见且重要的与吸烟相关的肺部疾病。成熟的吸入药物治疗方法（包括长效支气管扩张剂）具有经过验证的临床记录。然而，其作用的生理学基础仍在研究中。这项研究检查了慢性阻塞性肺病患者肺功能的一些生理变化以及对长效支气管扩张剂的反应，可能有助于解释为什么一些患者对治疗有反应而另一些患者则没有反应，从而导致更有针对性的治疗