Cognitive and Affective Dysfunctions in the Psychoses

精神病中的认知和情感功能障碍

• 批准号: 9087355
• 负责人: KEITH H NUECHTERLEIN
• 金额: $ 22.69万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-01 至 2018-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9087355
• 关键词: Affective; Cognitive; Functional disorder; Psychotic Disorders

DESCRIPTION (provided by applicant): This new postdoctoral clinical research training program focuses on developing research scientists who focus on cognitive and affective dysfunctions in psychotic disorders. The program will utilize a training model that emphasizes the skills needed to bring concepts and paradigms from cognitive science and cognitive, social, and affective neuroscience into patient- oriented, clinical research on core deficits in neurocognition, social cognition, and emotion in schizophrenia and related psychoses. Direct mentoring interactions with both clinical investigators and cognitive scientists/neuroscientists wil be a key feature of this program, with the focus being on development and implementation of clinical research with individuals with psychotic disorders and those at risk for such disorders. Co-mentoring by clinical investigators and cognitive scientists/neuroscientists will ensure the development of an understanding of the principles and methods for adapting paradigms for use in research on psychotic disorders. Additional training themes of this program will be an emphasis on research on the links between core cognitive and affective dysfunctions and functional outcome in psychotic disorders and on research that examines these processes across prodromal, first episode, and chronic phases of schizophrenia and related psychotic disorders. The new training program will focus on individuals with Ph.D. in clinical psychology, cognitive science, cognitive neuroscience, or affective neuroscience, and on individuals with an M.D. followed by a psychiatric residency who plan to pursue a research career. The training program will include (1) extensive hands-on training in the development and implementation of translational clinical research on cognitive and affective dysfunctions in psychotic disorders through interactions with the co-mentors, (2) a weekly Research Seminar on the Psychosis taught jointly by clinical researchers and cognitive scientists/neuroscientists, (3) a monthly Research Career Development Seminar, (4) an intensive regional career development retreat, (5) coursework, workshops, and laboratory training tailored to individual research interests, and (6) training in responsible conduct of research. The training will be closely interfaced with a number of clinical research opportunities that allow access to research participants with schizophrenia and related psychotic disorders.

描述（由申请人提供）：这个新的博士后临床研究培训计划的重点是培养专注于精神障碍认知和情感功能障碍的研究科学家。该项目将采用一种培训模式，强调将认知科学和认知、社会和情感神经科学的概念和范式引入以患者为导向的临床研究所需的技能，研究精神分裂症及相关疾病的神经认知、社会认知和情感的核心缺陷。精神病。与临床研究人员和认知科学家/神经科学家的直接指导互动将是该计划的一个关键特征，重点是针对精神障碍患者和有患此类疾病风险的人进行临床研究的开发和实施。临床研究人员和认知科学家/神经科学家的共同指导将确保人们理解精神障碍研究中采用范式的原则和方法。该计划的其他培训主题将重点研究精神障碍的核心认知和情感功能障碍与功能结果之间的联系，以及检查精神分裂症和相关精神障碍的前驱期、首发期和慢性期的这些过程的研究。新的培训计划将重点关注拥有博士学位的个人。临床心理学、认知科学、认知神经科学或情感神经科学领域的研究，以及拥有医学博士学位、随后计划从事研究职业的精神病学住院医师培训的个人。培训计划将包括（1）通过与共同导师的互动，在精神障碍认知和情感功能障碍的转化临床研究的开发和实施方面进行广泛的实践培训，（2）每周联合授课的精神病研究研讨会由临床研究人员和认知科学家/神经科学家主持，(3) 每月研究职业发展研讨会，(4) 密集的区域职业发展务虚会，(5) 根据个人研究兴趣量身定制的课程、研讨会和实验室培训，以及 (6) 培训以负责任的行为 研究。该培训将与许多临床研究机会紧密结合，使患有精神分裂症和相关精神病的研究参与者能够接触到这些机会。