RESOURCE/SERVICE CORE A - OCULAR IMAGING MODULE

资源/服务核心 A - 眼部成像模块

基本信息

批准号：
9153316
负责人：
William Joseph Dupps
金额：
$ 32.74万
依托单位：
CLEVELAND CLINIC LERNER COM-CWRU
依托单位国家：
美国
项目类别：
财政年份：
资助国家：
美国
起止时间：
至
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/9153316
关键词：
Angiography Animal Model Animals Anterior Center Core Grants Clinic Collaborations Core Grant Cornea Cryoultramicrotomy Data Diagnostic Disease Progression Eye Faculty Fluorescence Fostering Foundations Frozen Sections Funding Fundus Fundus photography Generations Glaucoma Goals Grant Image Imaging Techniques Imaging technology Immunohistochemistry Lasers Life Mind Modeling Mus Operative Surgical Procedures Ophthalmology Ophthalmoscopy Optical Coherence Tomography Oryctolagus cuniculus Paraffin Paraffin Embedding Plastic Embedding Process Productivity Protocols documentation Rattus Recruitment Activity Research Research Personnel Research Support Resources Retinal Diseases Risk Scanning Scientist Services Staining method Stains Supervision Talents Techniques Tissue Embedding Tissue Fixation Tissue imaging Tissues Transmission Electron Microscopy Vision Vision research Visual system structure Zebrafish abstracting cellular imaging experience faculty research imaging modality in vivo in vivo imaging innovation microscopic imaging programs ranpirnase sample fixation tissue processing treatment planning

项目摘要

Abstract Ocular Imaging Module The Ocular Imaging Module will provide a variety of imaging modalities to the investigators involved in this P30 Core Grant for Vision Research. The module includes live animal (in vivo) imaging with slit lamp and fundus photography, scanning laser ophthalmoscopy (SLO) and optical coherence tomography (OCT). It also supports tissue and cellular imaging (ex vivo) support, providing routine and specialized tissue fixation techniques, paraffin and plastic tissue embedding, sectioning (paraffin and Cryo) and staining for immunohistochemistry. Microscope imaging techniques include bright field, dark field, differential interference contrast (DIC), fluorescence, and transmission electron microscopy (TEM). It also provides help and advice with the morphometric analysis of generated images. Access to this core module will support NEI R01 funded investigators, help newly recruited investigators obtain data for NEI R01 grant submissions, foster collaborative interactions between RO1 funded investigators and newly recruited investigators, attract investigators from other departments to research on the visual system and be a valuable departmental resource in attracting additional vision scientists to our program as we expand our research faculty.

抽象的眼部成像模块眼部成像模块将为患者提供多种成像方式参与这项 P30 视觉研究核心资助的研究人员。该模块包括使用裂隙灯和眼底摄影、扫描激光对活体动物（活体）成像检眼镜检查 (SLO) 和光学相干断层扫描 (OCT)。它还支持组织和细胞成像（离体）支持，提供常规和特殊组织固定技术、石蜡和塑料组织包埋、切片（石蜡和冷冻）和免疫组织化学染色。显微镜成像技术包括明亮场、暗场、微分干涉衬度 (DIC)、荧光和透射电子显微镜（TEM）。它还提供形态测量方面的帮助和建议分析生成的图像。访问该核心模块将支持 NEI R01 资助研究人员，帮助新招募的研究人员获取 NEI R01 资助的数据提交材料，促进 RO1 资助的研究人员和新招募调查员，吸引其他部门的调查员参与研究视觉系统并成为吸引额外视觉的宝贵部门资源随着我们扩大研究队伍，科学家们加入到我们的项目中。