Soluble Epoxide Hydrolase as a Target for Ischemic Cardioprotection

可溶性环氧化物水解酶作为缺血性心脏保护的靶标

• 批准号: 7784461
• 负责人: Donna M Van Winkle
• 金额: --
• 依托单位: PORTLAND VA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7784461
• 关键词: Acids; Acute; Acute myocardial infarction; Adrenergic Agents; Adverse effects; American; American Heart Association; Arachidonic Acids; Biochemical; Biological Assay; Cardiac; Cardiac Myocytes; Cardiovascular Diseases; Cardiovascular system; Catheters; Cause of Death; Cell Death; Cells; Cessation of life; Clinical; Coronary; Coronary heart disease; Cytochrome P450; Data; Detection; Development; Diabetes Mellitus; Enzymes; Epoxide hydrolase; Evaluation; Expenditure; Gene Deletion; Glucose; Health; Healthcare; Heart; Heart Diseases; Hypertension; Immunohistochemistry; In Vitro; Incidence; Infarction; Injury; Ischemia; Isomerism; Knockout Mice; Left; Ligation; Measurement; Mediating; Medical; Metabolism; Methods; Molecular; Molecular Biology; Morbidity - disease rate; Mus; Myocardial; Myocardial Infarction; Myocardial Ischemia; Nerve Fibers; Neurons; Obesity; Oxygen; Pathway interactions; Patients; Personal Satisfaction; Pharmaceutical Preparations; Policies; Population; Post-Traumatic Stress Disorders; Process; Prophylactic treatment; Propidium Diiodide; Prospective Studies; Reperfusion Therapy; Research; Risk Factors; Role; Signal Transduction; Simulate; Staining method; Stains; Stress; Testing; Therapeutic; Transgenic Organisms; Translations; Ventricular; Veterans; Woman; adrenergic; cardiovascular risk factor; clinical practice; clinically relevant; combat; cost; demographics; deprivation; heart disease risk; improved; in vivo; inhibitor/antagonist; liquid chromatography mass spectrometry; male; men; mortality; mouse model; myocardial infarct sizing; novel strategies; research study; tool; triphenyltetrazolium; uptake; young adult