The Role of IgE in Autoimmune Skin Diseases

IgE 在自身免疫性皮肤病中的作用

• 批准号: 8195977
• 负责人: JANET A FAIRLEY
• 金额: --
• 依托单位: IOWA CITY VA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8195977
• 关键词: Advanced Development; Affinity; Affinity Chromatography; American; Antibodies; Antigens; Area; Autoantibodies; Autoimmune Diseases; Autoimmune Process; Autoimmunity; Basophils; Binding; Binding Sites; Biological Assay; Blood; Bulla; Bullous Pemphigoid; Cell Degranulation; Cell Line; Cell model; Cell surface; Cells; Chemotaxis; Collagen Type XVII; Confocal Microscopy; Cryoultramicrotomy; Cutaneous; Cytokine Signaling; Dendritic Cells; Dermal; Development; Disease; Disease model; Electron Microscopy; Enzyme-Linked Immunosorbent Assay; Epitopes; Event; Funding; Goals; Histamine Release; Human; IgE; IgE Receptors; Immunoblotting; Immunofluorescence Immunologic; Immunoglobulin G; Immunologics; Immunosuppressive Agents; In Vitro; Inflammation Mediators; Inflammatory; Inflammatory Response; Knowledge; Label; Laboratories; Lead; Lesion; Lesion by Stage; Liquid substance; Maps; Measures; Mediating; Microscopy; Modeling; Monitor; Monoclonal Antibodies; Morbidity - disease rate; Morphology; Mus; Pathogenesis; Pathogenicity; Patients; Peptides; Phase; Pilot Projects; Play; Process; Production; Proteins; Reaction; Resolution; Role; Serum; Skin; Source; Steroids; Surface; Testing; Therapeutic Intervention; Time; Tissues; Veterans; Work; Xenograft procedure; anti-IgE; antigen binding; base; conventional therapy; cytokine; disease characteristic; eosinophil; improved; in vitro Model; insight; keratinocyte; light microscopy; mast cell; mortality; mouse model; omalizumab; receptor; receptor expression; skin disorder; synthetic polymer Bioplex