Research Training in Gastroenterology

胃肠病学研究培训

• 批准号: 7855979
• 负责人: JEAN-PIERRE RAUFMAN
• 金额: $ 36.49万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7855979
• 关键词: Gastroenterology; Research Training

DESCRIPTION (provided by applicant): This renewal application for T32 DK067872, Research Training in Gastroenterology at the University of Maryland, Baltimore, requests 5 yrs of funding for 3 predoctoral and 5 postdoctoral (MD, PhD, MD/PhD) trainees. Overall goals of this program are unchanged; to seek and prepare talented trainees for academic careers in Gl by offering an integrated, Interdisciplinary curriculum that emphasizes mucosal biology & immunology, cell signaling & proliferation, enteric pathogens & vaccine development, and clinical research. School of Medicine entities represented by faculty with strong NIH funding cut across departmental lines to include Medicine, Pediatrics, Surgery, Microbiology & Immunology, Biochemistry & Molecular Biology, and Epidemiology & Preventive Medicine. Broad-based training opportunities allow predoctoral trainees to obtain PhD or MD/PhD degrees and postdoctoral trainees to earn MS, MPH or PhD degrees. Four research tracks (Cell Signaling & Proliferation, Mucosal Immunology & Microbiology, Epithelial Cell Biology, and Clinical & Translational Science) are directed by accomplished senior investigators and comprised of highly productive, experienced mentors who interact both within and amongst these tracks. Trainees devote a minimum of 2 yrs in lab- or patient-based research guided by faculty with exceptional mentorship and research credentials. In its initial period of funding, the program was highly successful; all training slots were filled, trainee retention was 100%, and productivity was outstanding. Both predoctoral T32 trainees who completed training qualified for the PhD degree. Of 8 postdoctoral fellows completing training, 4 are completing clinical training and 4 are Assistant Professors pursuing basic or clinical research in academic Medicine or Pediatrics (1 supported by and another with pending NIDDK K08 awards). This T32 program is extraordinarily diverse; of 15 trainees (2005-10), 10 (66%) are women; 3 (20%) are African American; and 2 (13%) are Hispanic. During the past 4 years, the program matured and grew by adding funded, productive faculty with strong mentoring credentials, and by innovation (e.g. adding Junior Faculty members, to 'mentor future mentors', and offering a Ph.D. Program for Clinicians). PUBLIC HEALTH RELEVANCE: Increasingly competitive research funding and lucrative practice opportunities discourage trainees from careers in gastroenterology research. The overall goal of this program is to seek and nurture talented pre- and postdoctoral trainees preparing for academic careers in gastroenterology by offering an integrated, interdisciplinary, individualized curriculum in both basic and clinical digestive diseases-related research.

描述（由申请人提供）：此 T32 DK067872（巴尔的摩马里兰大学胃肠病学研究培训）的续签申请要求为 3 名博士前和 5 名博士后（MD、PhD、MD/PhD）学员提供 5 年的资助。该计划的总体目标不变；通过提供强调粘膜生物学和免疫学、细胞信号传导和增殖、肠道病原体和疫苗开发以及临床研究的综合跨学科课程，寻找并为 GL 的学术职业做好准备。医学院实体以拥有 NIH 雄厚资金的教师为代表，跨院系，包括医学、儿科、外科、微生物学与免疫学、生物化学与分子生物学以及流行病学与预防医学。基础广泛的培训机会使博士前学员能够获得博士学位或医学博士/博士学位，博士后学员能够获得硕士学位、公共卫生硕士或博士学位。四个研究方向（细胞信号传导与增殖、粘膜免疫学与微生物学、上皮细胞生物学以及临床与转化科学）由卓有成就的高级研究人员指导，并由高产、经验丰富的导师组成，他们在这些方向内和之间进行互动。学员在具有卓越指导和研究资格的教师的指导下，投入至少 2 年的实验室或基于患者的研究。在资助的最初阶段，该计划非常成功；所有培训名额均已满，学员保留率为 100%，生产力非常出色。完成培训的博士前T32学员均获得博士学位。在完成培训的 8 名博士后研究员中，4 名正在完成临床培训，4 名是助理教授，从事学术医学或儿科的基础或临床研究（其中 1 名得到 NIDDK K08 奖项的支持，另一名正在等待 NIDDK K08 奖项）。这个T32项目非常多样化；在 15 名受训者中（2005-10 年），10 名（66%）是女性； 3 (20%) 是非裔美国人； 2 名 (13%) 是西班牙裔。在过去的 4 年里，该项目通过增加受资助、富有成效、具有强大指导资格的教师队伍以及创新（例如，增加初级教师成员来“指导未来的导师”，并为临床医生提供博士学位课程）而成熟和发展。 。 公共卫生相关性：日益竞争的研究经费和利润丰厚的实践机会阻碍了学员从事胃肠病学研究职业。该项目的总体目标是通过提供基础和临床消化疾病相关研究的综合、跨学科、个性化课程，寻找和培养有才华的博士前和博士后学员，为胃肠病学的学术生涯做好准备。