Anxiety Vulnerability and Smoking Cessation

焦虑脆弱性和戒烟

• 批准号: 8115929
• 负责人: Kirsten Johnson Langdon
• 金额: $ 3.82万
• 依托单位: UNIVERSITY OF VERMONT & ST AGRIC COLLEGE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2012-07-01
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8115929
• 关键词: Abstinence; Address; Affect; Affective; Anxiety; Anxiety Disorders; Attention; Basic Science; Behavioral; Cigarette Smoker; Clinical; Cognitive; Development; Disease; Emotions; Fright; Future; Health; Individual Differences; Investigation; Knowledge; Lead; Link; Literature; Maintenance; Maps; Mediating; Mental Depression; Methodology; Modeling; National Institute of Mental Health; Nicotine Withdrawal; Outcome; Panic; Pathway interactions; Persons; Pharmaceutical Preparations; Play; Populations at Risk; Post-Traumatic Stress Disorders; Prevalence; Process; Psyche structure; Public Health; Relapse; Reporting; Research; Research Proposals; Role; Smoker; Smoking; Smoking Behavior; Smoking Cessation Intervention; Specific qualifier value; Technology; Testing; Theoretical model; Time; Tobacco Dependence; Tobacco use; Translating; Withdrawal Symptom; Work; base; cigarette smoking; clinically significant; coping; experience; indexing; innovation; neglect; programs; smoking cessation; success

DESCRIPTION (provided by applicant): The primary objectives of the current proposal are as follows: 1.a. To test the hypothesis that smokers characterized by higher compared to lower Anxiety Sensitivity (AS) will demonstrate less success in a self-guided cessation attempt, as indexed by: (1.a.1) Shorter time to first smoking lapse; (1.a.2) Lower point-prevalence abstinence at one, two, four, and 12 weeks post-quit date. 1.b. To test the hypothesis that the association between AS and lapse/relapse to smoking is mediated by the specified emotion and smoking-based processes, including: (1.b.1) Greater levels of negative affect intensity during the cessation attempt; (1.b.2) Greater levels of nicotine withdrawal symptom intensity during the cessation attempt. PUBLIC HEALTH RELEVANCE: The present proposal fills a needed clinically- and theoretically-relevant gap in the smoking- psychiatric literature, as recently espoused by the current NIMH smoking-psychiatric vulnerability report (Ziedonis et al., in press). Indeed, results of the proposed study will directly inform AS-smoking models, and serve more generally as an illustration of how specific anxiety-related processes serve to maintain smoking behavior. The proposed investigation represents a clinically significant and innovative test for a program of research aimed at understanding the mechanisms underlying smoking lapse and relapse.

描述（由申请人提供）：当前提案的主要目标如下： 1.a．为了检验以下假设：与较低焦虑敏感性 (AS) 相比，吸烟者在自我引导戒烟尝试中表现出的成功率较低，其索引如下： (1.a.1) 首次戒烟时间较短； (1.a.2) 戒烟后 1、2、4 和 12 周的戒烟流行率较低。 1.b.检验 AS 与戒烟/复吸之间的关联是由特定情绪和基于吸烟的过程介导的假设，包括： (1.b.1) 尝试戒烟期间负面情绪强度更高； (1.b.2) 尝试戒烟期间尼古丁戒断症状强度更高。公共健康相关性：本提案填补了吸烟精神病学文献中所需的临床和理论相关空白，正如最新的 NIMH 吸烟精神病学脆弱性报告（Ziedonis 等人，出版中）所支持的那样。事实上，这项研究的结果将直接为 AS 吸烟模型提供信息，并更广泛地说明特定的焦虑相关过程如何维持吸烟行为。拟议的研究代表了一项具有临床意义和创新性的测试，旨在了解戒烟和复吸的机制。

项目成果

Relations between pain-related anxiety, tobacco dependence, and barriers to quitting among a community-based sample of daily smokers.

基于社区的日常吸烟者样本中与疼痛相关的焦虑、烟草依赖和戒烟障碍之间的关系。

• DOI: 10.1016/j.addbeh.2014.11.032
• 发表时间: 2015-03
• 期刊: Addictive behaviors
• 影响因子: 4.4
• 作者: Ditre, Joseph W.;Langdon, Kirsten J.;Kosiba, Jesse D.;Zale, Emily L.;Zvolensky, Michael J.
• 通讯作者: Zvolensky, Michael J.

Quit-attempt history: relation to current levels of emotional vulnerability among adult cigarette users.

戒烟尝试历史：与成年吸烟者当前情绪脆弱程度的关系。

• 发表时间: 2009-07
• 作者: Zvolensky, Michael J;Johnson, Kirsten A;Leyro, Teresa M;Hogan, Julianna;Tursi, Lauren
• 通讯作者: Tursi, Lauren

Dispositional Mindful Attention in Relation to Negative Affect, Tobacco Withdrawal, and Expired Carbon Monoxide On and After Quit Day.

戒烟日及戒烟后与负面影响、戒烟和过期一氧化碳相关的性格性正念关注。

• 发表时间: 2018
• 作者: Paulus, Daniel J;Langdon, Kirsten J;Wetter, David W;Zvolensky, Michael J
• 通讯作者: Zvolensky, Michael J

Financial strain and cognitive-based smoking processes: The explanatory role of depressive symptoms among adult daily smokers.

财务压力和基于认知的吸烟过程：成年每日吸烟者抑郁症状的解释作用。

• 发表时间: 2017-07
• 影响因子: 4.4
• 作者: Robles, Zuzuky;Anjum, Sahar;Garey, Lorra;Kauffman, Brooke Y;Rodríguez;Langdon, Kirsten J;Neighbors, Clayton;Reitzel, Lorraine R;Zvolensky, Michael J
• 通讯作者: Zvolensky, Michael J

Differential effect of sex on pain severity and smoking behavior and processes.

性别对疼痛严重程度以及吸烟行为和过程的不同影响。

• 发表时间: 2019
• 影响因子: 4.4
• 作者: Smit, Tanya;Garey, Lorra;Langdon, Kirsten J;Ditre, Joseph W;Rogers, Andrew H;Orr, Michael F;Zvolensky, Michael J
• 通讯作者: Zvolensky, Michael J