Brain, Blood, and Iron: advances in the cell biology of neurodegeneration

脑、血液和铁：神经变性细胞生物学的进展

• 批准号: 7803482
• 负责人: RUTH Helen WALKER
• 金额: $ 3.3万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-03-01 至 2011-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7803482
• 关键词: Affect; Aging; Apoptosis; Area; Autophagocytosis; Basal Ganglia; Biology; Blood; Brain; Cell Death; Cellular biology; Chorea Acanthocytosis Syndrome; Clinical; Collaborations; Consensus; Discipline; Disease; Educational workshop; Erythrocytes; Erythropoiesis; Fostering; Functional disorder; Future; Genetic; Hereditary Disease; Homeostasis; Iron; Knowledge; Laboratories; Light; Membrane; Membrane Protein Traffic; Methods; Nerve Degeneration; Neurobiology; Neurodegenerative Disorders; Participant; Patients; Proteins; Publishing; Research; Research Personnel; Research Priority; Resources; Scientist; Syndrome; United States National Institutes of Health; Work; career; interest; iron metabolism; meetings

DESCRIPTION (provided by applicant): The neuroacanthocytosis (NA) and neurodegeneration with brain iron accumulation (NBIA) syndromes are two groups of very rare genetic disorders, characterized by neurodegeneration affecting primarily the basal ganglia. Clinical, laboratory and neuropathological features suggest common methods of cell death. The proposed meeting will bring together researchers from a variety of fields which are likely to shed light upon the pathophysiology of these disorders.

描述（由申请人提供）：神经棘红细胞增多症（NA）和脑铁积累神经变性（NBIA）综合征是两组非常罕见的遗传性疾病，其特征是神经变性主要影响基底神经节。临床、实验室和神经病理学特征表明细胞死亡的常见方法。拟议的会议将汇集来自各个领域的研究人员，他们可能会阐明这些疾病的病理生理学。