CANCER RESEARCH CENTER

癌症研究中心

基本信息

批准号：
8166211
负责人：
SURANGANIE DHARMAWARDHANE
金额：
$ 18.74万
依托单位：
UNIVERSIDAD CENTRAL DEL CARIBE
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-07-01 至 2011-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8166211
关键词：
Area Biomedical Research Cancer Center Cell Nucleus Cells Clinical Collaborations Communities Computer Retrieval of Information on Scientific Projects Database Development Disease Faculty Fostering Funding Genomics Goals Grant Group Meetings Hispanics Institution Journals Malignant Neoplasms Minority NCI Center for Cancer Research Pathology Patients Pilot Projects Prevention Preventive Protein Array Analysis Recording of previous events Recruitment Activity Research Research Infrastructure Research Personnel Research Support Research Training Resources Series Source Testing Therapeutic Therapeutic Agents Time Tissues Training Translational Research Underrepresented Minority United States National Institutes of Health anticancer research cancer prevention cancer therapy efficacy testing malignant breast neoplasm member molecular marker mouse model next generation novel novel therapeutics programs repository

项目摘要

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. UCC has a successful history of training underrepresented minorities and conducting basic biomedical research. For the first time, we propose a disease-oriented center focused on cancer research that has clear potential to support the institutional research agenda of fostering translational research. Currently, UCC cancer investigators pursue basic and translational research on dietary compounds as breast cancer preventives, development of novel therapeutic agents for breast cancer, and identification of molecular markers for metastatic breast cancer. This research program is expected to be nurtured and expanded by the proposed cancer center. The OBJECTIVE of the proposed Cancer Research Center is to build cancer research capacity at UCC and increase minority participation in cancer research by training the next generation of minority cancer researchers. To achieve this objective, the following SPECIFIC AIMS will be carried out: 1) Expand the infrastructure to conduct cancer research at UCC; 2) Increase the number of cancer researchers at UCC; 3) Develop translational and clinical cancer research at UCC; 4) Establish a seminar series on cancer research and continuation of the cancer group meetings and journal club; 5) Educate the community about cancer prevention/early testing; 6) Support a Pilot Project from a junior faculty member. The center will be led by a senior researcher and will be organized into three main areas: 1) Testing the efficacy of novel cancer therapeutics in cell and mouse models, 2) genomic and protein array analysis of cancer pathology, 3) establishment of a cancer tissue repository from patients of mainly Hispanic origin. The GOAL of the Cancer Research Center is to facilitate translational research in the prevention and treatment of cancer. In collaboration with the RCMI/SRDU, we will recruit two faculty members while the Cancer Research Center will recruit one postdoctoral trainee and one technician to support the research of the faculty. This will reinforce and jumpstart our ultimate goal of creating a nucleus of active cancer researchers.

该子项目是利用该技术的众多研究子项目之一资源由 NIH/NCRR 资助的中心拨款提供。子项目和研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金，因此可以在其他 CRISP 条目中表示。列出的机构是对于中心来说，它不一定是研究者的机构。 UCC 在培训代表性不足的少数群体和开展基础生物医学研究方面拥有成功的历史。我们首次提议建立一个以疾病为导向的中心，专注于癌症研究，该中心具有支持促进转化研究的机构研究议程的明显潜力。目前，UCC 癌症研究人员致力于膳食化合物作为乳腺癌预防剂的基础和转化研究、新型乳腺癌治疗药物的开发以及转移性乳腺癌分子标记物的鉴定。该研究计划预计将由拟议的癌症中心培育和扩大。拟建癌症研究中心的目标是建设 UCC 的癌症研究能力，并通过培训下一代少数族裔癌症研究人员来增加少数族裔对癌症研究的参与。为了实现这一目标，将实施以下具体目标： 1) 扩大 UCC 开展癌症研究的基础设施； 2）增加UCC癌症研究人员的数量； 3) 在UCC开展转化和临床癌症研究； 4) 建立癌症研究系列研讨会并继续癌症小组会议和期刊俱乐部； 5) 对社区进行有关癌症预防/早期检测的教育； 6) 支持初级教员的试点项目。该中心将由一名高级研究员领导，分为三个主要领域：1）在细胞和小鼠模型中测试新型癌症疗法的功效，2）癌症病理学的基因组和蛋白质阵列分析，3）建立癌症模型主要来自西班牙裔患者的组织库。癌症研究中心的目标是促进癌症预防和治疗的转化研究。我们将与 RCMI/SRDU 合作，招募两名教职人员，而癌症研究中心将招募一名博士后实习生和一名技术人员，以支持教职人员的研究。这将加强并推动我们创建活跃癌症研究人员核心的最终目标。