Division of Chemical Toxicology Symposia at the 266th National ACS Meeting

第266届全国ACS会议化学毒理学研讨会分部

基本信息

批准号：
10753870
负责人：
Michael A Trakselis
金额：
$ 0.8万
依托单位：
BAYLOR UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-06-16 至 2024-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10753870
关键词：
Academia Affect Aging American Area Artificial Intelligence Award Biochemistry Biology Chemical Exposure Chemical Models Chemicals Chemistry Collaborations Communication Communities Complement Data Disease Disparity Drug Interactions Drug toxicity Environmental Health Faculty Fostering Funding Goals Health Human Industrialization Industry Journals Knowledge Leadership Learning Link Measures Metabolism Mission Molecular National Institute of Environmental Health Sciences Oral Outcome Pharmaceutical Chemistry Pharmaceutical Preparations Policies Postdoctoral Fellow Process Publishing Research Research Methodology Research Personnel Role San Francisco Scientist Societies Students System Testing Toxic effect Toxicology Travel United States National Institutes of Health Vulnerable Populations Writing career career development drug efficacy environmental agent environmental chemistry graduate student improved in vitro Model interest medical specialties meetings member novel organ growth organ on a chip posters programs response skill acquisition student mentoring symposium welfare

项目摘要

Project Summary/Abstract The goal of this application is to obtain support for the American Chemical Society Division of Chemical Toxicology (TOXI) at the 266th 2023 National Meeting program, which will be held August 13-17, 2023, in San Francisco, CA. The mission of the Division of Chemical Toxicology is to improve human health and public welfare by promoting the understanding of chemical mechanisms that govern disease processes and the toxicity of drugs, environmental agents, and endogenous chemicals. Our goals include providing a forum for communicating research in the field of chemical toxicology, encouraging research in chemical mechanisms of toxicity, and facilitating connections between academia, industry, and policy in scientific areas of mutual interest. We are also committed to developing the leadership and professional development skills of scientists at all levels. Thus, the requested funds will be used to support travel awards and expenses for graduate students, postdoctoral scholars, and junior faculty. The overall TOXI program is organized around the theme of “Toxicological Predictions, Markers, and Outcomes Affecting Human Health” and complements the National Meeting theme of Harnessing the Power of Data. The program includes five thematic symposia, which will feature invited oral presentations by a diverse group of established and emerging investigators with a range of perspectives on each topic. The five thematic symposia are: (1) “Application of Augmented Artificial Intelligence in Toxicology Metabolism Prediction”, co-promoted by the Divisions of Chemical Information (CINF) and Medicinal Chemistry (MEDI), will explore the role of augmented AI in predicting toxic metabolites; (2) “Toxicity & Drug-Drug Interactions Resulting from Inhibition of Transporters”, co-promoted with MEDI, will examine the impact of inhibiting transporters to regulate drug efficacies; (3) “Advanced in vitro Models for Chemical Toxicity,” co-promoted with MEDI, focuses on recent progress in development of organ-on-chip systems on testing chemical toxicity; (4) “Linking Toxicology and Human Health Through the Exposome”, copromoted with the Divisions of Biological Chemistry (BIOL) and Environmental Chemistry (ENVR), describes recent advances in measuring lifetime of chemical exposures and disparities in vulnerable populations; and (5) “Endogenous Metabolites in Aging and Disease”, copromoted with BIOL, focuses on the chemistry and biology that underly cellular responses to misregulated formation of endogenous metabolites. The scientific program is clearly aligned with the mission of NIEHS.

项目概要/摘要此应用程序的目标是获得美国化学会化学分部的支持第 266 届 2023 年全国会议计划中的毒理学 (TOXI) 将于 2023 年 8 月 13 日至 17 日在加利福尼亚州旧金山市化学毒理学部的使命是改善人类健康和通过促进对控制疾病过程的化学机制的理解和公共福利我们的目标包括提供药物、环境因素和内源性化学物质的毒性。交流化学毒理学领域研究、鼓励化学研究的论坛毒性机制，并促进学术界、工业界和科学政策之间的联系我们还致力于发展领导力和专业发展。因此，所申请的资金将用于支持旅行奖励和研究生、博士后学者和初级教师的总体费用为 TOXI 计划。围绕“影响人类健康的毒理学预测、标记和结果”主题组织并补充了全国会议主题“利用数据的力量”，该计划包括。五场专题研讨会，由不同领域的知名人士和知名人士受邀进行口头演讲新兴研究者对每个主题都有不同的观点，五个专题研讨会是：(1) “增强人工智能在毒理学代谢预测中的应用”，由化学信息 (CINF) 和药物化学 (MEDI) 部门将探讨增强人工智能预测有毒代谢物；(2)“抑制引起的毒性和药物相互作用” 与 MEDI 共同发起的“转运蛋白”项目将研究抑制转运蛋白对药物调节的影响（3）与MEDI共同发起的“先进的化学毒性体外模型”，重点关注近年来 (4) “将毒理学与与生物化学部门（BIOL）和环境化学 (ENVR)，描述了测量化学品暴露寿命的最新进展以及弱势群体的差异；(5)“衰老和疾病中的内源代谢物”，与 BIOL 共同推广，重点关注细胞反应的化学和生物学内源性代谢物的形成失调。科学计划显然与 NIEHS 的使命。