2023 Central Nervous System Injury and Repair Gordon Research Conference and Seminar

2023中枢神经系统损伤与修复戈登研究会议暨研讨会

• 批准号: 10753737
• 负责人: Yishi Jin
• 金额: $ 2.15万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-05 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10753737
• 关键词: Acceleration; Achievement; Advocate; Age; Age Distribution; Animal Model; Applications Grants; Area; Atmosphere; Basic Science; Biological Models; Bladder Dysfunction; COVID-19 pandemic; Cells; Cellular biology; Central Nervous System; Charities; Clinical Research; Communication; Consensus; Data; Development; Disadvantaged; Disease; Education; Ensure; Environment; Ethnic Origin; Face; Faculty; Fostering; Friends; Future; Gender; Geographic Distribution; Geographic Locations; Goals; Hour; Immune; Industrialization; Industry; Injury; International; Interruption; Interview; Italy; Life; Mediation; Medical; Mentors; Molecular; Molecular Biology; Natural regeneration; Neuroglia; Neurons; Numbness; Occupations; Oral; Pain; Paralysed; Participant; Patient Care; Patients; Persons; Physicians; Positioning Attribute; Postdoctoral Fellow; Publishing; Recovery of Function; Renaissance; Reporting; Research; Research Institute; Research Personnel; Science; Scientist; Series; Sexual Dysfunction; Social Interaction; Spinal cord injury; Time; Translations; Underrepresented Minority; Universities; Woman; Work; age group; axon injury; career; career development; cell type; central nervous system injury; clinical application; clinical practice; combinatorial; disability; effective therapy; experience; graduate student; injury and repair; innovation; interest; meetings; nerve injury; nerve repair; neural circuit; neuronal circuitry; novel; peer networks; posters; programs; repaired; response to injury; restoration; social; stem cells; symposium

Project Summary: The 2023 Gordon Research Conference (GRC) series, entitled “Central Nervous System Injury and Repair”, together with its accompanying Gordon Research Seminar (GRS), will bring together interactional researchers at all levels to discuss progress and challenges for CNS injury, regeneration, and repair, with particular emphasis on spinal cord injury. Spinal cord injury is a major medical challenge since it leaves millions of people worldwide paralyzed and with loss of sensation, cardiorespiratory, bladder, and sexual dysfunction as well as pain for their lifetime. Despite many years of efforts, effective treatment remains lacking. This is in part due to the complexity of this disease where in addition to the damage of axons, spinal cord injury leads to profound changes in the cellular and molecular environment, involving neurons, glia, immune cells, and other cell types. An emerging consensus is that combinatorial approaches targeting multiple cellular and molecular aspects of the injury response will be necessary to treat spinal cord injury and induce functional recovery. At this conference, we will showcase the most exciting and cutting-edge scientific progress in this field, with the goal of collectively accelerating the discovery and translation of treatments that will lead to functional recovery. The conference speakers cover broad topics from basic mechanisms in neuronal circuitry and axonal injury in animal models, clinical application, and progress in stem cell programming, through to clinical practice and patient care. The discussion will be encouraged both formally in the scientific sessions and informally during poster sessions and time set aside for social interactions. The accompanying GRS will serve as an interactive forum for trainees to communicate their research and broaden their peer network. The GRC will also feature a Power Hour, open to all attendees, to discuss challenges we face, particularly women, underrepresented minorities, disadvantaged researchers, and trainees. We expect a large attendance from basic and physician-scientists, as well as representation from industry. We also anticipate a breadth of diversity across gender, ethnicity, disability, age, and geographical location that will ensure a broad and inclusive communication of the scientific content.

项目概要： 2023 年戈登研究会议 (GRC) 系列题为“中枢神经系统损伤与修复”，连同其附带的戈登研究研讨会 (GRS)，将汇集各个级别的互动研究人员，讨论中枢神经系统损伤、再生、脊髓损伤是一项重大的医学挑战，因为它导致全世界数百万人瘫痪，并导致感觉丧失、心肺功能障碍、膀胱功能障碍和性功能障碍。尽管经过多年的努力，仍然缺乏有效的治疗方法，部分原因是这种疾病的复杂性，除了轴突损伤之外，脊髓损伤还会导致细胞和分子环境发生深刻的变化。涉及神经元、神经胶质、免疫细胞和其他细胞类型的一个新兴共识是，针对损伤反应的多个细胞和分子方面的组合方法对于治疗脊髓损伤和诱导功能恢复是必要的。展示该领域最令人兴奋和最前沿的科学进展会议发言人涵盖了动物模型中神经回路和轴突损伤的基本机制、临床应用和干细胞编程进展等广泛主题。讨论将在科学会议中进行正式讨论，在海报会议中进行非正式讨论，并为社交互动留出时间，作为一个互动论坛，供学员交流他们的研究并扩大他们的研究范围。 GRC 也将具有特色。向所有与会者开放的 Power Hour，讨论我们面临的挑战，特别是女性、弱势群体、弱势研究人员和实习生。我们预计会有大量基础医学科学家和行业代表参加。跨性别、种族、残疾、年龄和地理位置的多样性，这将确保科学内容的广泛和包容性传播。