The Helicase and Nucleic Acid-based Machines Conference: Structure, Mechanism, Regulation and Roles in Human Diseases

解旋酶和核酸机器会议：结构、机制、调节和在人类疾病中的作用

基本信息

批准号：
10753877
负责人：
Elizabeth J Tran
金额：
$ 1.05万
依托单位：
FEDERATION OF AMER SOC FOR EXPER BIOLOGY
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-07-13 至 2024-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10753877
关键词：
Address Advocacy Aging American Award Biochemical Biochemistry Biological Biological Models Biology Biophysics COVID-19 pandemic Career Mobility Cellular biology Collaborations Communities Complement DNA DNA Damage DNA Repair Data Dedications Development Discipline Disease Education Environment Enzymes Equilibrium Europe Faculty Fostering Funding Gender Gene Expression Gene Expression Process Gene Expression Regulation Genetic Genomics Goals Health Human Immunologic Deficiency Syndromes Infertility International Linear Programming Location Malignant Neoplasms Massachusetts Mind Mission Mutation Nucleic Acids Participant Personal Satisfaction Positioning Attribute Postdoctoral Fellow Predisposition Published Comment RNA RNA Helicase Regulation Reporting Research Research Personnel Role Schedule Science Scientist Services Site Societies Structure Students Techniques Time Training Travel Underrepresented Minority United States Virus Replication Woman career career development career life balance career networking design equity, diversity, and inclusion experience genome integrity graduate student helicase human disease innovation insight meetings member minority scientist nervous system disorder next generation novel strategies posters programs repaired social engagement summer research symposium therapeutic target translocase treatment strategy

项目摘要

Project Summary/Abstract The goal of this application is to obtain funding to support the biennial FASEB conference Helicases and Nucleic Acid-Based Machines: Structure, mechanism, regulation, and roles in human diseases, July 16-20, 2023, in Southbridge, MA. This will be the 14th meeting of this conference. The FASEB mission is to “advance health and well-being by promoting research and education in biological and biomedical sciences through collaborative advocacy and service to our member societies and their members”. The 2023 conference will focus on the roles of DNA and RNA helicases, which define fundamental processes of gene expression, genome integrity, and viral replication. Two training sessions are planned for our attendees: one “Meet- the-Experts” session, which will include a range of topics from starting your own lab to work-life balance and a diversity, equity, and inclusion (DEI) keynote address that will be positioned during dinner for maximum attendance. The requested funds will support limited travel for invited speakers and travel awards for students and postdocs, junior faculty, and our invited DEI speaker. Nine topical sessions are scheduled which range from post-translational gene regulation to DNA damage and repair, all of which are intimately connected to human diseases. This is especially true for cancer subsets as DNA damage, inefficient or incomplete repair, and aberrant gene expression are well known hallmarks.

项目概要/摘要此申请的目标是获得资金来支持两年一度的 FASEB 会议解旋酶和核酸机器：结构、机制、调节和作用人类疾病，2023 年 7 月 16 日至 20 日，在马萨诸塞州绍斯布里奇举行，这将是该会议的第 14 次会议。 FASEB 的使命是“通过促进研究促进健康和福祉”。通过协作宣传和服务进行生物和生物医学科学教育 2023 年会议将重点讨论以下方面的作用： DNA 和 RNA 解旋酶，定义基因表达、基因组的基本过程为我们的参加者计划了两场培训课程：一场是“见面-” “专家”会议，其中包括从建立自己的实验室到工作生活等一系列主题平衡和多样性、公平性和包容性 (DEI) 主题演讲将定位晚餐期间尽可能多地出席，所请求的资金将用于支持有限的旅行。为学生、博士后、初级教师以及我们受邀的 DEI 提供特邀演讲者和旅行奖励安排了九个主题会议，范围包括翻译后基因。 DNA损伤和修复的调控，所有这些都与人类疾病密切相关。对于癌症亚型尤其如此，因为 DNA 损伤、修复效率低下或不完整，以及异常的基因表达是众所周知的标志。