The Gastrointestinal Epithelium Conference - Interface with the Outside World

胃肠上皮会议 - 与外界的接口

• 批准号: 10753753
• 负责人: Mark R Frey
• 金额: $ 4.2万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10753753
• 关键词: Area; Autophagocytosis; Basic Science; Biology; Biomedical Research; Cell Communication; Cells; Cellular biology; Clinical; Collaborations; Colon; Committee Members; Communication; Communities; Complement; Consultations; Data; Development; Developmental Biology; Digestive System Disorders; Diné Nation; Discipline; Disease; Drug Delivery Systems; Educational workshop; Ensure; Environment; Epithelium; Esophagus; Female; Friends; Funding; Future; Gastrointestinal Physiology; Gastrointestinal tract structure; Goals; Guanosine Triphosphate Phosphohydrolases; Health; Homeostasis; Hypoxia; In Vitro; Individual; Inflammation; Inflammatory Bowel Diseases; Intestines; Investigation; Laboratories; Length; Malignant Neoplasms; Mentorship; Metabolism; Methodology; Methods; Microbiology; Molecular; Molecular Biology; National Institute of Diabetes and Digestive and Kidney Diseases; Natural regeneration; Neurobiology; Oral; Parents; Participant; Physicians; Physiological; Process; Proliferating; Reagent; Request for Applications; Research; Research Personnel; Resolution; Role; Schedule; Science; Scientist; Sensory; Signal Transduction; Signaling Molecule; Site; Small Intestines; Stomach; Students; Systemic disease; Time; Underrepresented Minority; Underrepresented Populations; United States National Institutes of Health; Woman; bench to bedside; career; career development; cell motility; clinically significant; design; gastrointestinal; gastrointestinal epithelium; genetic manipulation; in vivo Model; injury and repair; innovation; insight; interest; intestinal barrier; lectures; live cell imaging; meetings; member; pathogen; posters; programs; response; response to injury; stem cell homeostasis; stem cells; symposium; trafficking

Project summary/abstract This application requests partial support for a FASEB Scientific Research Conference entitled “Gastrointestinal Epithelium: Interface with the Outside World” that is scheduled for September 17-21, 2023 in Steamboat Springs, CO. The meeting will convene a diverse group of speakers, including many women, underrepresented minorities, and young investigators, to discuss the biology of the gastrointestinal epithelium and its role in homeostasis and disease. The keynote presentations plus seven lecture sessions will address gastrointestinal stem cell homeostasis and plasticity in response to injury/disease; development and differentiation of the epithelium; injury repair, proliferation, and regeneration in the esophagus, stomach, small intestine, and colon; cell-cell interactions; host-pathogen interactions; intestinal barrier; hypoxia, inflammation and IBD; and cancer. Ample time will be set aside for discussions amongst participants, and the presentation of unpublished data will be prioritized. There will also be two poster sessions as well as several career development activities for early career investigators and trainees, as well as opportunities to promote the visibility of these individuals who represent the future of the field. We have assembled an innovative program with committed participation from leaders with diverse expertise within GI-related research fields. Overall, in an intimate and secluded setting that encourages informal interactions between scientists at all levels, we provide an innovative approach to the exchange of ideas and synthesis of science that will move the field of GI research forward. The conference will have high impact as the program spans basic science discovery to clinical significance for GI health and disease. It is therefore expected that the meeting will provide new insights not only into basic gastrointestinal physiology, neurobiology, developmental biology and microbiology, but also how to treat, and ultimately cure, a wide variety of digestive disease states.

项目概要/摘要 本申请请求对题为“胃肠道疾病”的 FASEB 科学研究会议提供部分支持 上皮细胞：与外界的接口”定于 2023 年 9 月 17 日至 21 日在斯廷博特举行 科罗拉多州斯普林斯。会议将召集多元化的发言者，其中包括许多女性，但代表性不足 少数族裔和年轻的研究人员，讨论胃肠上皮的生物学及其在 主题演讲和七场讲座将讨论胃肠道问题。 干细胞稳态和可塑性以响应损伤/疾病的发育和分化； 上皮；食道、胃、小肠和结肠的损伤修复、增殖和再生； 细胞-细胞相互作用；宿主-病原体相互作用；缺氧、炎症和癌症； 将留出充足的时间供参与者讨论，并展示未发表的数据 还将优先安排两次海报会议以及一些早期职业发展活动。 职业调查员和实习生，以及提高这些人的知名度的机会 代表该领域的未来，我们制定了一项创新计划，并得到了来自各方的坚定参与。 总体而言，在亲密而僻静的环境中，具有地理相关研究领域不同专业知识的领导者。 为了鼓励各级科学家之间的非正式互动，我们提供了一种创新方法 会议将进行思想交流和科学综合，推动地理标志研究领域向前发展。 具有重大影响，因为该计划涵盖基础科学发现和对胃肠道健康的临床意义 因此，预计这次会议不仅会提供关于基本胃肠道疾病的新见解。 生理学、神经生物学、发育生物学和微生物学，还包括如何治疗并最终治愈 多种消化系统疾病状态。